Table 2 Diagnostic criteria for adult-onset Still’s disease [4, 5]
Yamaguchi’s criteria [4] | Fautrel’s criteria [5] |
|---|---|
Major criteria | Major criteria |
Fever > 39 °C, lasting 1 week or longer | Spiking fever ≥ 39 °C |
Arthralgia or arthritis, lasting 2 weeks or longer | Arthralgia |
Typical rash | Transient erythema |
Leukocytosis > 10,000/mm3 with > 80% polymorphonuclear cells | Pharyngitis |
Polymorphonuclear cells ≥ 80% | |
Glycosylated ferritin ≤ 20% | |
Minor criteria | Minor criteria |
Sore throat | Maculopapular rash |
Recent development of significant lymphadenopathy | Leukocytosis ≥ 10,000/mm3 |
Hepatomegaly or splenomegaly | |
Abnormal liver function tests | |
Negative tests for antinuclear antibody (IF) and rheumatoid factor (IgM) | |
Exclusion criteria | Exclusion criteria |
Infections | Infections |
Malignancies (mainly malignant lymphoma) | Malignancies (mainly malignant lymphoma) |
Other rheumatic disease (mainly systemic vasculitides) | Other rheumatic disease (mainly systemic vasculitides) |
Five or more criteria are required, a minimum of two should be major criteria | Four or more criteria are required with minimum three major criteria |