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Table 5 Reported thrombotic microangiopathy cases: comparative table

From: Acute kidney injury secondary to thrombotic microangiopathy associated with idiopathic hypereosinophilic syndrome: a case report and review of the literature

Demographics Our patient Historical 1 [3] Historical 2 [3] Historical 3 [4]
Sex Male Male Male Male
Age, years 63 15 26 24
Race Caucasian African American Caucasian Caucasian
CBC at admission
 Hemoglobin 12.0–17.5 g/dl 10.0 9.8 13.3 10.7
 Platelets 140–450 × 103/μl 235a 76 101 130
 White cell count 4.5–11.0 × 103/μl 22.2 23.7 14.7 23.5
Differential count, %
 Neutrophils 1.50–7.50 × 103/μl 4.8 8.3 6.7 Not available
 Lymphocytes 1.50–3.70 × 103/μl 0.9 2.8 2.6 Not available
 Monocytes 0.20–1.00 × 103/μl 0.2 0.7 0.4 Not available
 Eosinophils 0.00–0.50 × 103/μl 16.2 11.1 4.9 18.3
Schistocytes Positive Not available Positive Positive
Renal function test at admission
 Creatinine 0.61–1.24 mg/dl 1.3 10.9 2.2 1.81
GFR 56 Not available 57 50
 Percentage eosinophils in bone marrow 60% 80% 44% 37%
 Renal biopsy Glomerular capillary thrombosis
Mesangiolysis
Endotheliosis
Eosinophilic infiltrate
Arterial thrombosis
Mesangiolysis
Eosinophilic infiltrate
Arteriolar thrombosis
Glomerular capillary thrombosis
Eosinophilic infiltrate
Arteriolar thrombosis
Glomerular capillary thrombosis
Eosinophilic infiltrate
Urinalysis
 Proteinuria Negative Present Present Present
 Red blood cells/high-power field 20 50 Not available 100
 Eosinophils/high-power field None None 7 None
 Treatment Prednisone Prednisone
Rituximab
Prednisone
Imatinib
Imatinib
 Follow-up At 2 months At 6 months At 12 months At 12 months
 Creatinine 0.61–1.24 mg/dl 1.18 5.2 1.8 1.7
  1. *Our patient’s platelets at baseline: 377–348 × 103/μl
  2. CBC Complete Blood Count, GFR Glomerular Filtration Rate