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Table 1 Summary of thoracic radiotherapy with implantable cardioverter-defibrillator in vivo studies

From: Inevitable high-dose irradiation to lead of implantable cardioverter defibrillator in small cell lung cancer: a case report

Study No. of patients RT dose/fraction
(Gy)
Energy
(MV)
ICD dose
(maximum dose, Gy)
Used dosimeter Follow-up duration (mo) Outcome
Thomas et al. [6] 1 56/28 18 < 0.5 NR >  1.6 Reset to fallback mode
Nemec et al. [7] 1 59.4/33 NR NR NR NR Runaway ICD, resulting in polyform VT, implement of cardiopulmonary resuscitation during RT
Zaremba et al.a [8] 5 37 6/18 37 NR 2.5–13.4 Reset to backup mode (n = 1)
Ahmed et al. [9] 1 69.6/36 15 52.4 NR 6 No failure
Scobioala et al.b [10] 1 25.2/14 (conformal RT)
35/7 (SBRT)
6/15
6
15.85 TLD 16 No failure
Hudson et al. [11] 2 70/32 6/18 6.8 TLD NR No failure
Our patient 1 60/30 10 2.23 MOSFET >  36 No failure
  1. Abbreviations: ICD Implantable cardioverter-defibrillator, MOSFET Metal oxide semiconductor field effect transistor, NR Not recorded, RT Radiotherapy, SBRT Stereotactic body radiotherapy, TLD Thermoluminescent detector, VT Ventricular tachycardia
  2. aThe study was performed in ICD-implanted pigs
  3. bTreatment combined with conformal RT and SBRT