Inevitable high-dose irradiation to lead of implantable cardioverter defibrillator in small cell lung cancer: a case report

Table 1 Summary of thoracic radiotherapy with implantable cardioverter-defibrillator in vivo studies

Study	No. of patients	RT dose/fraction (Gy)	Energy (MV)	ICD dose (maximum dose, Gy)	Used dosimeter	Follow-up duration (mo)	Outcome
Thomas et al. [6]	1	56/28	18	< 0.5	NR	> 1.6	Reset to fallback mode
Nemec et al. [7]	1	59.4/33	NR	NR	NR	NR	Runaway ICD, resulting in polyform VT, implement of cardiopulmonary resuscitation during RT
Zaremba et al.^a [8]	5	37	6/18	37	NR	2.5–13.4	Reset to backup mode (n = 1)
Ahmed et al. [9]	1	69.6/36	15	52.4	NR	6	No failure
Scobioala et al.^b [10]	1	25.2/14 (conformal RT) 35/7 (SBRT)	6/15 6	15.85	TLD	16	No failure
Hudson et al. [11]	2	70/32	6/18	6.8	TLD	NR	No failure
Our patient	1	60/30	10	2.23	MOSFET	> 36	No failure

Abbreviations: ICD Implantable cardioverter-defibrillator, MOSFET Metal oxide semiconductor field effect transistor, NR Not recorded, RT Radiotherapy, SBRT Stereotactic body radiotherapy, TLD Thermoluminescent detector, VT Ventricular tachycardia
^aThe study was performed in ICD-implanted pigs
^bTreatment combined with conformal RT and SBRT

ISSN: 1752-1947