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Table 1 Laboratory data on admission

From: Denosumab improves clinical manifestations of hypophosphatemic osteomalacia by adefovir-induced Fanconi syndrome: a case report

    Reference range
Chemistry
 AST 12 U/L 13–30
 ALT 7 U/L 10–42
 T-Bil 0.5 mg/dl 0.4–1.5
 LDH 141 U/L 124–222
 ALP 1223 U/L 106–322
 ALP1 3 %  
 ALP2 + ALP3 91 %  
 ALP5 6 %  
 LAP 49 U/L 30–70
 gGTP 12 U/L 13–64
 ChE 267 U/L 215–464
 TP 6.6 g/dl 6.6–8.1
 Alb 4.1 g/dl 4.1–5.1
 BUN 14 mg/dl 8.0–20.0
 Cre 1.44 mg/dl 0.65–1.07
 eGFR 40.2 ml/min/1.73m2  
 UA 1.5 mg/dl 3.7–7.0
 Na 143 mEq/L 138–145
 K 4 mEq/L 3.6–4.8
 Cl 113 mEq/L 101–108
 Ca 8.5 mg/dl 8.8–10.1
 IP 1.9 mg/dl 2.7–4.6
 Glucose 93 mg/dl 55–110
 HbA1c 4.8 % 4.3–5.8
 CRP 0.1 mg/dl ≤ 0.14
 Serum β2-microglobulin 3.5 mg/dl  
Hepatitis marker
 Hbs-Ag 250 IU/ml < 0.05
 HBs-Ag 0.4 S/CO < 1.0
 HBe-Ab 99.6 %Inh < 50.0
Hematology
 WBC 5200 /μl 3300–8600
 RBC 447 104/μl 4.35–5.55
 Hb 16.5 g/dl 13.7–16.8
 Hct 47.6 % 40.7–50.1
 Plt 16.3 104/μl 15.8–34.8
Bone metabolic parameters
 TRACP-5b 781 mU/dl 170–590
 Bone ALP 112 μg/L 3.7–20.9
 Deoxypyridinoline 6.7 nmol/mmol Cre 2.1–5.4
 U-NTx 216.1 nmol BCE/mmol Cr 13.0–66.2
 calcitonin 16 pg/ml < 9.52
 intact-PTH 43.6 pg/ml 8.7–79.6
 PTHrP < 1.1 pmol/L < 1.1
 1,25(OH)2 Vit.D3 26.4 pg/ml 20.0–60.0
 FGF23 < 5 pg/ml  
Immunology
 Antinuclear antibody 20 times < 20
 C3 74 mg/dl 65–135
 C4 13 mg/dl 13–53
 CH50 41 U/ml 30–50
 IgG 1031 mg/dl 680–1620
 IgA 301 mg/dl 84–438
 IgM 87 mg/dl 57–288
 IgE 3 IU/ml < 295
 Serum immunoelectrophoresis M protein (−)  
 Urinary immunoelectrophoresis BJ protein (+)  
Blood gas analysis
 pH 7.328   7.350–7.450
 PCO2 40.3 mmHg 35.0–45.0
 PO2 110 mmHg 85.0–105.0
 HCO3- 20.5 mmol/L 23.0–28.0
 BE −4.7 mmol/L −4.6
 AG 4.8 mmol/L 8.0–12.0
Urinalysis
 pH 6.5   
 U-glucose 100 mg/dl  
 U-blood   
 BJ-protein +   
 U- total protein 1.3 g/g Cr  
 Urinary NAG 7.8 IU/L 0.3–11.5
  16.3 IU/g Cr  
 Urinary β2-microglobulin 138,885 μg/g Cr  
 Na 73 mEq/L  
 K 24 mEq/L  
 Cl 91 mEq/L  
 Ca 29.4 mg/dl  
 IP 43 mg/dl  
 UA 30 mg/dl  
 Cre 48 mg/dl  
 %TRP 41.59 %  
 FEUA 46.3 %  
  1. Abbreviations: AG Anion gap, Alb Albumin, ALP Alkaline phosphatase, ALT alanine aminotransferase, AST aspartate aminotransferase, BCE Bone collagen equivalents, BE Base excess, BJ protein Bence-Jones protein, BUN Blood urea nitrogen, CH50 Total hemolytic complement, ChE Cholinesterase, Cre Creatinine, CRP C-reactive protein, eGFR Estimated glomerular filtration rate, FEUA Fractional excretion of uric acid, FGF23 Fibroblast growth factor 23, gGTP γ-Glutamyl transpeptidase, Hb Hemoglobin, HbA1c Hemoglobin A1c, HBe-Ab Hepatitis B e antigen antibody, Hbs-Ag Hepatitis B surface antigen, HCO3 Bicarbonate, Hct Hematocrit, Ig Immunoglobulin, IP inorganic phosphorus, LAP Leukocyte alkaline phosphatase, LDH Lactate dehydrogenase, NAG N-acetyl-β-D-glucosaminidase, NTx Cross-linked N-telopeptide of type I collagen, PCO2 Partial pressure of carbon dioxide, Plt Platelets, PO2 Partial pressure of oxygen, PTH Parathyroid hormone, PTHrP Parathyroid hormone-related protein, RBC Red blood cells, T-Bil Total bilirubin, TP Total protein, TRACP-5b Tartrate-resistant acid phosphatase 5b, %TRP Percentage tubular reabsorption of phosphate, UA Urinalysis, WBC White blood cells