Fig. 1

Deep seated, wall-penetrating rectal carcinoma (a, arrow, magnetic resonance imaging (MRI) with multiple bilateral liver metastases (b, arrow, computed tomography (CT) before treatment in April 2012. The patient reached partial remission after two cycles of cisplatin/irinotecan (c, residual metastasis in segment I with an arrow, CT) in June 2012 and complete remission after six cycles (d, arrow: no evidence of macroscopic metastasis in segment I, CT) in October 2012. View of segment I showing post-treatment recurrence in February 2013 (e, arrow, MRI) and status 5 years after stereotactic body radiotherapy and chemotherapy in February 2018 (f, no evidence of vital tumor: arrow, MRI)