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Fig. 1 | Journal of Medical Case Reports

Fig. 1

From: Proctalgia and constipation secondary to hypertrophic polyglucosan inclusion body myopathy of the internal anal sphincter: a case report

Fig. 1

Investigations confirming internal anal sphincter myopathy. a Endoanal ultrasound. The internal anal sphincter is thickened with a diameter greater than 5 mm. EAS external anal sphincter, IAS internal anal sphincter. b Anal manometry with resting pressure exceeding 200 mmHg in internal anal sphincter myopathy. c Anal squeeze pressure lower than maximum resting pressures seen in anal sphincter myopathy. d Histology of the internal anal sphincter biopsy showing vacuolation of smooth muscle containing periodic acid–Schiff-positive polyglucosan body inclusions (hematoxylin and eosin, periodic acid–Schiff, × 20 magnification)

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