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Table 2 Application of Yamaguchi clinical criteria in presented patient

From: Noncaseating suppurative granulomatous lymphadenitis in adult onset Still’s disease – a diagnostic dilemma in a tuberculosis-endemic region: a case report

Yamaguchi criteria Patient’s characteristics
Major Yamaguchi criteria
 Fever of at least 39 °C lasting at least 1 week +
 Arthralgias or arthritis lasting 2 weeks or longer +
 Typical rash (maculopapular, nonpruritic) during febrile episodes
 Leukocytosis (10,000/μL or greater) with at least 80% granulocytes
Minor Yamaguchi criteria
 Sore throat
 Lymphadenopathy +
 Hepatomegaly or splenomegaly
 Abnormal liver function studies +
 Negative antinuclear antibodies and rheumatoid factor +
 Infection Done
 Malignancies: mainly lymphoproliferative Done
 Other rheumatological disorders Done
  1. Yamaguchi criteria require the presence of five features, with at least two being major diagnostic criteria