From: Ivermectin-induced fixed drug eruption in an elderly Cameroonian: a case report
Questions | Yes | No | DK |
---|---|---|---|
1. Are there previous conclusive reports on this reaction? | + 1 | – | – |
2. Did the adverse event appear after the suspected drug was administered? | +2 | – | – |
3. Did the adverse reaction improve when the drug was discontinued or a specific antagonist was administered? | + 1 | – | – |
4. Did the adverse event reappear when the drug was re-administered? | – | – | 0 |
5. Are there alternative causes (other than the drug) that could on their own have caused the reaction? | − 1 | – | – |
6. Did the reaction reappear when a placebo was given? | – | + 1 | – |
7. Was the drug detected in blood (or other fluids) in concentrations known to be toxic? | – | 0 | – |
8. Was the reaction more severe when the dose was increased or less severe when the dose was decreased? | + 1 | – | – |
9. Did the patient have a similar reaction to the same or similar drugs in any previous exposure? | + 1 | – | – |
10. Was the adverse event confirmed by any objective evidence? | + 1 | – | – |