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Table 1 Different types of neuronal ceroid lipofuscinosis

From: Novel in-frame deletion in MFSD8 gene revealed by trio whole exome sequencing in an Iranian affected with neuronal ceroid lipofuscinosis type 7: a case report

Types of NCLs Pattern Onset Gene Chromosome location
NCL1 AR Infantile
Adulthood (mild form)
PTT1/CLN1 1p32
NCL2 AR Late infantile TPP1/CLN2 11p15.5
NCL3   Juvenile CLN3 16p12.1
NCL4 AR
AD
Adulthood CLN6
DNAJC5
15q21-q23
20q13.33
NCL5 AR Late infantile
Adulthood (mild form)
CLN5 13q21.1-q32
NCL6 AR Late infantile CLN6 15q21.q23
NCL7 AR Late infantile CLN7/MFSD8 4q28.1-q28.2
NCL8 AR Late infantile CLN8 8p23.3
NCL9 AR Juvenile Unknown Unknown
NCL10 AR Newborn
Adulthood
(mild form)
CLN10/CTSD 1p15.5
  1. AD autosomal dominant, AR autosomal recessive, NCL neuronal ceroid lipofuscinosis