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Table 2 Comparison of all studies on patients with aplastic anemia and celiac disease

From: Celiac disease associated with aplastic anemia in a 6-year-old girl: a case report and review of the literature

Study Grey-Davies and colleagues [3] Salmeron and colleagues [12] Maheshwari and colleagues [8] Kumar and colleagues [9] Badyal and colleagues [5] Present study 2017
No. of cases 3 5 1 1 1 1
Age (years) 47, 37, 23 NA 13 10 9 6
Gender All female NA Male Male Male Female
Country England England India India India Pakistan
Infection One patient had Aspergillus and Pseudomonas infection and died NA No history of infection present No history of infection present No history of infection present Had infection with Pseudomonas recently with a history of infections.
Small intestinal biopsy Partial, subtotal, and total villous atrophy Subtotal villous atrophy Total villous atrophy Subtotal villous atrophy Biopsy not done because of active GI bleed and low platelet counts Total villous atrophy with increased intraepithelial lymphocytes
IgA-tTG levels Not mentioned NA >205 IU/mL 100 IU/mL >105 IU/mL 370 IU/mL
Bone marrow examination and biopsy Aplastic anemia Aplastic anemia Aplastic anemia Not done Aplastic anemia Aplastic anemia
  1. NA, not available; IgA, gamma A immunoglobulin; IgA -tTG, gamma A immunoglobulin tissue transglutaminase; GI, gastrointestinal; IU/ml, International units per millilitre