Skip to main content

Table 2 Comparison of all studies on patients with aplastic anemia and celiac disease

From: Celiac disease associated with aplastic anemia in a 6-year-old girl: a case report and review of the literature

Study

Grey-Davies and colleagues [3]

Salmeron and colleagues [12]

Maheshwari and colleagues [8]

Kumar and colleagues [9]

Badyal and colleagues [5]

Present study 2017

No. of cases

3

5

1

1

1

1

Age (years)

47, 37, 23

NA

13

10

9

6

Gender

All female

NA

Male

Male

Male

Female

Country

England

England

India

India

India

Pakistan

Infection

One patient had Aspergillus and Pseudomonas infection and died

NA

No history of infection present

No history of infection present

No history of infection present

Had infection with Pseudomonas recently with a history of infections.

Small intestinal biopsy

Partial, subtotal, and total villous atrophy

Subtotal villous atrophy

Total villous atrophy

Subtotal villous atrophy

Biopsy not done because of active GI bleed and low platelet counts

Total villous atrophy with increased intraepithelial lymphocytes

IgA-tTG levels

Not mentioned

NA

>205 IU/mL

100 IU/mL

>105 IU/mL

370 IU/mL

Bone marrow examination and biopsy

Aplastic anemia

Aplastic anemia

Aplastic anemia

Not done

Aplastic anemia

Aplastic anemia

  1. NA, not available; IgA, gamma A immunoglobulin; IgA -tTG, gamma A immunoglobulin tissue transglutaminase; GI, gastrointestinal; IU/ml, International units per millilitre