Study | Grey-Davies and colleagues [3] | Salmeron and colleagues [12] | Maheshwari and colleagues [8] | Kumar and colleagues [9] | Badyal and colleagues [5] | Present study 2017 |
---|---|---|---|---|---|---|
No. of cases | 3 | 5 | 1 | 1 | 1 | 1 |
Age (years) | 47, 37, 23 | NA | 13 | 10 | 9 | 6 |
Gender | All female | NA | Male | Male | Male | Female |
Country | England | England | India | India | India | Pakistan |
Infection | One patient had Aspergillus and Pseudomonas infection and died | NA | No history of infection present | No history of infection present | No history of infection present | Had infection with Pseudomonas recently with a history of infections. |
Small intestinal biopsy | Partial, subtotal, and total villous atrophy | Subtotal villous atrophy | Total villous atrophy | Subtotal villous atrophy | Biopsy not done because of active GI bleed and low platelet counts | Total villous atrophy with increased intraepithelial lymphocytes |
IgA-tTG levels | Not mentioned | NA | >205Â IU/mL | 100Â IU/mL | >105Â IU/mL | 370Â IU/mL |
Bone marrow examination and biopsy | Aplastic anemia | Aplastic anemia | Aplastic anemia | Not done | Aplastic anemia | Aplastic anemia |