From: Crescentic glomerular nephritis associated with rheumatoid arthritis: a case report
Examinations | Results | ||
---|---|---|---|
Urine full report | Protein 2+ Pus cells: 5–10/HPF Red blood cells: moderately full field Few granular casts present | ||
Twenty-four-hour urinary protein excretion | 2 g/24 hours | ||
Dysmorphic red blood cells | 17% | ||
Serum creatinine | 2 months before presentation: 88 μmol/L | On admission: 389 μmol/L | Posttreatment: 110 μmol/L |
Serum electrolytes | Sodium: 138 mmol/L | ||
Potassium: 4.1 mmol/L | |||
Inflammatory markers | ESR: 110 mm in first hour | ||
CRP: 45 mg/dl | |||
Fasting blood sugar | 95 mg/dl | ||
Abdominal ultrasound | Normal-sized kidneys with acute parenchymal changes and mild ascites No organomegaly | ||
Renal biopsy | Renal parenchyma containing 20 glomeruli showing diffuse proliferative glomerular nephritis, with 14 of 20 glomeruli showing cellular crescents, and result of Congo red staining was negative Immune fixation not done, owing to its unavailability | ||
Immunological markers | Rheumatoid factor: high titer (120 IU/ml) | ||
ANA- and dsDNA-negative | |||
ANCA-negative (perinuclear and cytoplasmic) | |||
Complement C3: 98 mg/dl (normal range 90–180) | |||
Complement C4: 21 mg/dl (normal range 10–40) | |||
ASOT: <200 U/ml | |||
Cryoglobulins: not detected | |||
Other secondary causes screening | Hepatitis B surface antigen-negative | ||
Hepatitis C antibody-negative | |||
HIV-1- and HIV-2-negative | |||
Malignancy screening: negative | |||
Screening tests done: chest x-ray, ultrasound thyroid, abdomen and pelvis, mammogram, gastrointestinal endoscopy | |||
Liver profile | Albumin: 28 g/L Globulin: 33 g/L | ||
Transaminases and bilirubin: normal |