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Table 1 Patient’s laboratory examination results

From: Crescentic glomerular nephritis associated with rheumatoid arthritis: a case report

Examinations

Results

Urine full report

Protein 2+ Pus cells: 5–10/HPF Red blood cells: moderately full field Few granular casts present

Twenty-four-hour urinary protein excretion

2 g/24 hours

Dysmorphic red blood cells

17%

Serum creatinine

2 months before presentation: 88 μmol/L

On admission: 389 μmol/L

Posttreatment: 110 μmol/L

Serum electrolytes

Sodium: 138 mmol/L

Potassium: 4.1 mmol/L

Inflammatory markers

ESR: 110 mm in first hour

CRP: 45 mg/dl

Fasting blood sugar

95 mg/dl

Abdominal ultrasound

Normal-sized kidneys with acute parenchymal changes and mild ascites

No organomegaly

Renal biopsy

Renal parenchyma containing 20 glomeruli showing diffuse proliferative glomerular nephritis, with 14 of 20 glomeruli showing cellular crescents, and result of Congo red staining was negative

Immune fixation not done, owing to its unavailability

Immunological markers

Rheumatoid factor: high titer (120 IU/ml)

ANA- and dsDNA-negative

ANCA-negative (perinuclear and cytoplasmic)

Complement C3: 98 mg/dl (normal range 90–180)

Complement C4: 21 mg/dl (normal range 10–40)

ASOT: <200 U/ml

Cryoglobulins: not detected

Other secondary causes screening

Hepatitis B surface antigen-negative

Hepatitis C antibody-negative

HIV-1- and HIV-2-negative

Malignancy screening: negative

Screening tests done: chest x-ray, ultrasound thyroid, abdomen and pelvis, mammogram, gastrointestinal endoscopy

Liver profile

Albumin: 28 g/L

Globulin: 33 g/L

Transaminases and bilirubin: normal

  1. Abbreviations: ANA Antinuclear antibody, ANCA Antineutrophil cytoplasmic antibody, ASOT Antistreptolysin O titer, CRP C-reactive protein, dsDNA Double-stranded deoxyribonucleic acid, ESR Erythrocyte sedimentation rate, HIV Human immunodeficiency virus, HPF High-power field