Fig. 3
Schedule of chemotherapy, hemodialysis, and blood sampling. In the third and fourth chemotherapy cycles, cisplatin (15 mg/m2) and etoposide (75 mg/m2) was conducted daily from day 1 through to day 5. Hemodialysis was started 1 hour after infusions of these agents. Venous blood samples were collected five times each day: (1) before cisplatin infusion, (2) immediately after infusion, (3) before hemodialysis, (4) after hemodialysis, and (5) 4 hours after hemodialysis on days 1 to 5. In addition, blood was collected (6) before hemodialysis on day 8 once in each course. CDDP cisplatin, ETP etoposide, HD hemodialysis