Fig. 2

a Photomicrograph of the resected duodenal specimen shows irregular sequence of the tubular epithelium; hematoxylin and eosin (H&E), original magnification, ×20. b Hematoxylin and eosin (original magnification, ×100). c Immunohistological staining of foveolar epithelium for mucin 5AC (MUC5AC). No staining of the original duodenal epithelium. Brown cytoplasmic staining of the foveolar gastric metaplasia (blue arrows; magnification, ×20). d Immunohistological staining of goblet cell in duodenum mucin 2 (MUC2). No staining of the lesion. Brown staining of the original duodenal epithelium (magnification, ×20). e Mucin 2 (magnification, ×100). f Immunohistological staining of a malignant potential for p53. No staining of p53 (magnification, ×100). The circled within the panel denotes high power of H & E stained slide (a→b) and MUC2 (d→e)