Fig. 3

Hematoxylin and eosin-stained sections from core biopsy reveal renal cortex containing few glomeruli and expected number of renal tubules. Glomeruli (black arrows in a and b) and tubules (green arrows in a and b) show extensive coagulation necrosis, with few of the tubular cells having karyolytic nuclei. No viable glomerulus or tubule is discernible; however, the connective tissue framework is preserved. Sections also reveal necrosed blood vessels, including a necrosed and thrombosed intralobular artery (white arrow in a). Neutrophilic infiltrates are also present in the interstitium surrounding necrosed glomeruli and tubules