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Table 1 Patient’s timeline

From: Rare complication of bronchoesophageal fistula due to pulmonary mucormycosis after induction chemotherapy for acute myeloid leukemia: a case report

Day

Patient’s illness

1

Induction chemotherapy for acute myeloid leukemia (cytarabine + idarubicin)

Prophylactic antibiotics (ciprofloxacin)

3

White blood cell count reached it its nadir

13

Neutropenic fever developed

Right pleuritic chest pain with productive coughing and sticky sputum

Pneumonia developed

Changed to meropenem and vancomycin

17

Neutropenic fever persisted

Pneumonia aggregation

Exudative pleural effusion

Enterococcus faecium with resistance to vancomycin in pleural effusion

Meropenem and linezolid, and caspofungin

19

White blood cell count recovered within normal range

Complete remission for acute myeloid leukemia through bone marrow biopsy

Developed sudden cough that would become more severe after swallowing

Esophagram; thin fistula at the mid-esophagus and the right bronchus intermedius

Chest computed tomography imaging; extensive necrotizing pneumonia of the right lung and suspicious for a bronchoesophageal fistula

Bronchoscopy; hyperemic mucosa on right upper bronchus and brownish necrotic tissue in the middle lobe of his right lung

Esophagoscopy; a large linear defect of the esophageal wall

20

Mucormycosis confirmed

Amphotericin B instead of caspofungin

Sudden death due to hemoptysis