Fig. 3

Histopathological findings of the tumors. Upper part, histological findings of the segment 4 tumor. Upper left, a stroma-rich tumor was seen in the cirrhotic liver (hematoxylin and eosin stain; original magnification, ×40). Upper right, moderate disorder of the tubuloglandular structures was observed and cellular polarity was no longer maintained, suggesting that segment 4 tumor was composed of moderately differentiated adenocarcinoma (hematoxylin and eosin stain; original magnification, ×200). Lower part, histological findings of the segment 8 tumor. Lower left, a tumor with little stroma was seen in the cirrhotic liver (left half of the picture; hematoxylin and eosin stain; original magnification, ×200). Lower right, structural atypia was mild and cellular polarity was relatively maintained although sizes of the nuclei were varied in this tumor. The segment 8 tumor was diagnosed as well-differentiated hepatocellular carcinoma based on these findings (hematoxylin and eosin stain; original magnification, ×200)