Figure 1

Fundus photography and optical coherence tomography scans in the left eye (pre-ranibizumab) and the right eye (post-bevacizumab). (A, A’) Fundus autofluorescence, (B, B’) fluorescein angiography, (C, C’) optical coherence tomography; (A, B, C) right eye; (A’, B’, C’) left eye. The left eye images are before ranibizumab treatment. The right eye images are after three intravitreal bevacizumab injections (September 2008). The color fundus images (A-A’) show the macular involvement by the choroidal neovascularization (white arrowheads) mainly in the right eye with severe bleeding (gray arrowhead). The choroidal neovascularization is visible in both eyes by fluorescein angiography (white arrows in B and B’). The optical coherence tomography shows retinal pigment epithelium detachment in the right eye with subretinal fluid over the neovascularization (C). Initial retinal pigment epithelium interruption, intraretinal fluid and neuroretinal detachment are observable in the left eye (C’).