Skip to main content

Table 3 Results of multichannel impedance-pH monitoring during pucalopride-treatment[7]

From: Prucalopride reduces the number of reflux episodes and improves subjective symptoms in gastroesophageal reflux disease: a case series

  Patient 1 Patient 2 Patient 3 Patient 4
MII and/or pH monitoring during treatment with prucalopride Medication during monitoring: Medication during monitoring: Medication during monitoring: Medication during monitoring:
- Pantoprazole 40mg per day - Pantoprazole 40mg per day - Omeprazole 20mg per day - Prucalopride 2mg per day
+ Prucalopride 2mg per day + Prucalopride 2mg per day + Prucalopride 2mg per day  
Acid reflux time: 0.1% Acid reflux time: 0.9% Acid reflux time: 1.2% Acid reflux time: 1.9%
Overall reflux episodes: 46 Overall reflux episodes: 108 Overall reflux episodes: 83 Overall reflux episodes: 59
Mixed or liquid reflux episodes: 5 Mixed or liquid reflux episodes: 100 Mixed or liquid reflux episodes: 74 Mixed or liquid reflux episodes: 40
Gaseous reflux episodes: 41 Gaseous reflux episodes: 8 Gaseous reflux episodes: 9 Gaseous reflux episodes: 19
Acid reflux episodes: 17 Acid reflux episodes: 32 Acid reflux episodes: 26   39
Non- and/or weakly acid reflux episodes: 29 Non- and/or weakly acid reflux episodes: 76 Non- and/or weakly acid reflux episodes: 57 Acid reflux episodes: Non- and/or weakly acid reflux episodes: 20
*Scale 0 to10: 0 = none; 10 = unbearable Subjective symptom scores* Subjective symptom scores* Subjective symptom scores* Subjective symptom scores*
- Heartburn + Regurgitation: 3 - Heartburn + Regurgitation: 5 - Regurgitation: 3 - Heartburn, Globus, Bloating: 4
Limitation of daily life: 3 Limitation of daily life: 5 Limitation of daily life: 3 Limitation of daily life: 9
  SI: positive for heartburn and regurgitation SI: positive for heartburn, negative for regurgitation SI: negative for regurgitation SI: negative for heartburn, globus and bloating
  1. MII – multichannel impedance monitoring, SI – symptom index.
  2. Subjective symptom scores are based on the questionnaire previously described by Becker V et al.[7]. SAP, Symptom association probability; SI, Symptom index.