Figure 1
From: Identification of a novel COL2A1 mutation (c.1744G>A) in a Japanese family: a case report
Pedigree of our patient’s family. Members I-1, II-1, 3, 5 (gray) had complained of coxalgia during their lifetimes and are suspected of having had hip joint disease. Members II-9, III-3, 20 had been diagnosed with end-stage OA and member III-3, 20 had required total hip arthroplasty. Members III-6, 11, 15 had been diagnosed with AVN and required trochanteric osteotomy. The proband (IV-1) is indicated by the black arrow.