Table 1 Results of biochemical investigations at different time points during hospital stay
| Â | Investigation results on admission | Investigation results at diagnosis of valproate-induced hepatotoxicity | Investigation results during ventilation for hepatic encephalopathy | Investigation results at diagnosis of posterior reversible encephalopathy syndrome |
|---|---|---|---|---|
Hemoglobin (g/dL) | 13.0 | 13.2 | 12.8 | 10.0 |
White cell count (/L) | 7.6 × 109 | 28.0 × 109 | 33 × 109 | 19 × 109 |
Neutrophils (%) | 50% | 44% | 38% | 40% |
Lymphocytes (%) | 48% | 46% | 48% | 48% |
Eosinophils (%) | 2% | 10% | 14% | 12% |
Platelet count (/L) | 157 × 109 | 411 × 109 | 409 × 109 | 544 × 109 |
Alanine aminotransferase (U/L) | 18 | 625 | 1026 | 702 |
Aspartate aminotransferase (U/L) | 43 | 1199 | 2768 | 1024 |
Serum bilirubin (g/dL) | Â | 0.5 | 13.0 | 9.9 |
Serum albumin (g/dL) | Â | 2.9 | 2.3 | 3.2 |
Serum globulin (g/dL) | Â | 1.9 | 2.5 | 3.6 |
International normalized ratio | Â | 1.48 | 3.25 | 1.3 |
Serum alkaline phosphatase (U/L) | Â | 1839 | 1272 | 1043 |