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Table 1 Prognostic evaluation of neuroblastic tumorsa

From: Novel use of a Weerda laryngoscope for transoral excision of a cervical ganglioneuroma: a case report

International Neuroblastoma Pathology Classification

Tumor description

Original Shimada

classification

Prognostic group

Neuroblastoma

Schwannian stroma-poor

Stroma-poor

 

   Favorable

 

Favorable

Favorable

< 0.5 years

Poorly differentiating or differentiating and low or intermediate MKI tumor

  

1.5 to 5 years

Differentiating and low MKI tumor

  

   Unfavorable

 

Unfavorable

Unfavorable

< 1.5 years

Undifferentiated tumor

  
 

High MKI tumor

  

1.5 to 5 years

Undifferentiated or poorly differentiated tumor

  
 

Intermediate or high MKI tumor

  

≥ 5 years

All tumors

  

Ganglioneuroblastoma, intermixed

Schwannian stroma-rich

Stroma-rich intermixed (favorable)

Favorable

Ganglioneuroma

Schwannian stroma-dominant

 

Favorable

   Maturing

 

Well-differentiated (favorable)

 

   Mature

 

Ganglioneuroma

 

Ganglioneuroblastoma, nodular

Composite Schwannian stroma-rich/stroma-dominant and stroma-poor

Stroma-rich nodular

(unfavorable)

Unfavorable

  1. aMKI: mitosis-karyorrhexis index.