Table 1 Adverse drug reaction probability scale (Naranjo Scale) in the present case

1. Are there previous conclusive reports on this reaction?

0

2. Did the adverse event appear after the suspected drug was given?

2

3. Did the adverse reaction improve when the drug was discontinued or a specific antagonist was given?

0

4. Did the adverse reaction appear when the drug was readministered?

0

5. Are there alternative causes that could have caused the reaction?

2

6. Did the reaction reappear when a placebo was given?

0

7. Was the drug detected in any body fluid in toxic concentrations?

0

8. Was the reaction more severe when the dose was increased, or less severe when the dose was decreased?

0

9. Did the patient have a similar reaction to the same or similar drugs in any previous exposure?

0

10. Was the adverse event confirmed by any objective evidence?

1

Scoring

5