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Table 3 Reviewed cases of xanthogranulomaa

From: Xanthogranuloma of the intrasellar region presenting in pituitary dysfunction: a case report

Case

Author

Age/sex

Symptoms

Clinical findings

Radiological findings (MRI)

Tumor size (cm)

Time to operation

Tumor region

Follow-up

1

Present case

47/M

Headache

Body weight loss

Panhypopituitarism

Visual disturbance

T1:H/I, T2:CE:heterogeneous

Mixed-intensity solid tumor

1.2 × 1.8 × 1.5

5 M

Intrasellar

Required medical supplement

2

Reithmeier et al., 2002 [4]

51/M

Pallor

Loss of libido

Hypophyseal insufficiency

Visual dysfunction

T1:H, CE:heterogeneous

Unavailable

Unavailable

Intrasellar

Not described

3

Yonezawa et al., 2003 [5]

67/M

Headache

General fatigue

Appetite loss

Panhypopituitarism

T1:H, T2:L, heterogeneous:CE:

N

Mixed-intensity cystic tumor

Not described

3 M

Intrasellar

Doing well 3 months later

4

Burt et al., 2003 [6]

29/M

Headache

Nausea

Erectile dysfunction

Hypophyseal dysfunction

Visual defects

T1:H, T2:heterogeneous CE:heterogeneous

Mixed-intensity partially cystic tumor

1.8 × 1.5

3 W to 3 M

Suprasellar

Doing well 18 months later

5

 

26/M

Body weight loss

Lethargy

Panhypopituitarism

T1:H, T2:L, CE:N

Mixed-intensity cystic tumor

Not described

12 M

Intrasellar-suprasellar

Required medical supplement

6

Jung et al., 2005 [9]

57/F

Headache

Visual disturbance

T1:H, T2:L, CE:heterogeneous

Mixed-intensity solid tumor

2.0 × 2.0 × 2.5

12 M

Intrasellar-suprasellar

Not described

7

 

5/M

Weakness

Appetite loss

Headache

Hypothyroidism

Secondary adrenal insufficiency

Diabetes insipidus

T1, T2:heterogeneous

Mixed-intensity cystic tumor

2.6

5 W

Intrasellar-suprasellar

Not described

8

Liu et al., 2008 [22]

32/M

Consciousness disorder

Blurred vision

Disorientation

T1:H, T2:H and focal L

Mixed-intensity cystic tumor

3.4 × 3.8 × 4.2

2 D

Suprasellar

Doing well 6 months later

9

Sugata et al., 2009 [7]

26/M

Polyuria

General fatigue

Hypopituitarism

Visual disturbance

T1:I or L, T2:L, CE:heterogeneous

Mixed-intensity solid tumor

3.0

5 to 10 Y

Suprasellar

Required medical supplement

  1. aH, high intensity; L, low intensity; I, isointensity; heterogeneous, heterogeneous intensity; CE, gadolinium contrast enhancement; N, negative; Y, years; M, months; D, days; T1, T1-weighted; T2, T2-weighted.