Figure 2From: Severe brain atrophy after long-term survival seen in siblings with familial amyotrophic lateral sclerosis and a mutation in the optineurin gene: a case series Computed tomography scans of the younger sibling. At the age of 48 years (12 years after onset; 10 years after the initiation of mechanical ventilation) brain atrophy was apparent. Subsequently, brain atrophy progressed as in his elder sister. Y-Years; MV-mechanical ventilation.Back to article page