Table 1 Published data concerning chemotherapy regimens used in metastatic ameloblastoma

CR

Cycolphosphamide

Good functional

[11]

-M

Methotrexate

outcome

-Lung metastases

5 Fluorouracil

OR: 0%

CR

Vinblastine

Partial response: 50%

[13]

-M

Cisplatin

-Lung metastases

Bleomycin

CR

Adriamycin

Partial response

[12]

-W, 17 years old

Cisplatin

-Lung metastases

Cyclophosphamide

CR

1^st line: 5FU-Cisplatin

Progression disease after two cycles; repetitive partial response.

[9]

-W, 28 years old

2^nd line: Paclitaxel-

-Lung metastases

Carboplatin

CR

Cyclophosphamide

OR: 0%

[17]

-M, 46 years old

-Lung metastases + mediastinal adenopathies

CR

No chemotherapy

Stable disease during 18 months

[6]

-M, 55 years old

-Lung metastases

CR

No chemotherapy; surgery for removable metastases.

Survival: 54 years

[15]

-W, 39 years old

-Lung metastases

Review

Doxorubicin ± 5FU.

OR: 0%.

[14]

Outcome of chemotherapy in metastatic ameloblastoma.

Methotrexate ± cyclophosphamide

Blemomycin

5FU-Cisplatin

Vincristine

Prednisolone