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Table 1 Cases of RCC metastases to the orbit

From: Atypical presentations and rare metastatic sites of renal cell carcinoma: a review of case reports

Patient sex age at diagnosis

Location

Treatment of primary tumor

Interval between diagnosis of primary tumor and metastasis

(months)

Diagnosis of metastasis before primary treatment

Presenting symptoms

Metastases to other sites

m/54

Uvea

Nephrectomy

36

no

Eye vision problem

-

NA

Bilateral lacrimal gland

NA

NA

NA

NA

-

m/43

Choroidal and conjunctival

Nephrectomy

12

no

Left orbital pain

-

NA

Choroidal, ocular, extraocular, vitreous

Nephrectomy

96

no

Cataract

-

m/52

Choroidal

Nephrectomy

24

no

Eye vision problem

Lung

m/63

Eyelid

Nephrectomy/chemotherapy

NA

no

Upper lid tumor

Lung

m/58

Inferior rectus muscle

-

Metastasis first

yes

Proptosis and diplopia

-

f/NA

Lacrimal sac

Nephrectomy

NA

NA

Epiphora

-

m/73

Orbit

Nephrectomy

204

no

Epistaxis

Nasal cavity, ethmoidal sinus

m/67

Iris

Nephrectomy

NA

no

NA

-

m/58

Orbit

-

Metastasis first

yes

NA

-

f/23

Orbit

Nephrectomy

one

no

NA

-

f/60

Orbit

-

Metastasis first

yes

Proptosis

-

m/69

Orbit

-

Metastasis first

yes

Proptosis

-

m/66

Eyelid

Nephrectomy

15

no

NA

Lung, skin, brain

m/47

Eyelid

Nephrectomy

33

no

NA

Abdomen, skin, lung

m/59

Retroocular

-

Metastasis first

yes

Proptosis and diplopia

-

m/72

Conjuctival

-

Metastasis first

yes

Ulcerated lesion

-

m/70

Orbit

-

Metastasis first

yes

Cataract

-

  1. f: female; m: male; NA: not available