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Table 1 Reported cases of primary malignant melanoma of the adrenal gland

From: Primary melanoma of the adrenal gland: a case report and review of the literature

Reference

Year

Age

Sex

Location

Size

Clinical data

Treatment

Follow-up

Kniseley and Baggentoss [1]

1946

60

M

Left

8.5 cm × 4.5 cm × 4.5 cm

Back pain, abdominal mass, anorexia

Radiotherapy

Died two months after detection

Dick et al. [2]

1955

62

M

Right

17 cm × 12 cm × 10 cm

Painless, slowly growing mass

Surgery without specification

Died 15 months later

Sasidharan et al. [3]

1977

52

F

Left

13 cm × 10 cm × 5 cm

Asymptomatic; Well-defined, partly mobile, non-tender, globular lump confined to the left lumbar region

Adrenalectomy and nephrectomy

No follow-up

Carstens et al. [4]

1984

32

F

Left

14 cm × 9 cm × 5 cm

Pain in the left flank, weight loss

Adrenalectomy and nephrectomy

Died seven months later

Parker and Vincent [5]

1986

77

M

Right

 

Asymptomatic. Casual finding in prostatic patient. Extrinsic compression of the proximal right ureter and displacement of the collecting system and renal contour laterally.

Autopsy examination

Died two months after diagnosis

Dao et al. [6]

1990

46

F

Right

8 cm × 7 cm × 6 cm

Severe right flank pain

Adrenalectomy and nephrectomy

Died one month later

Amérigo et al. [7]

2000

24

F

Left

9 cm

Intense post-prandial epigastric pain and weight loss

Adrenalectomy and nephrectomy

Alive 46 months later

Zalatnai et al. [8]

2003

41

F

Left

7.3 cm × 6 cm

Nausea, mild weight loss, abdominal tenderness and constant left flank pain

Explorative laparotomy (non-resectable tumor)

Died three months later

Granero et al. [9]

2004

78

M

Right

11 cm

Right flank pain, fever, nausea and vomiting

Adrenalectomy, nephrectomy and splenectomy

Alive 12 months later

Liatsikos et al. [10]

2006

42

M

Left

5.5 cm × 6 cm

Mild flank pain, weight loss and anemia

Laparoscopic trans-peritoneal adrenalectomy

Alive 12 months later

Bastide et al. [11]

2006

33

M

Right

-

Right paroxystic lumbar pain, mass in the right flank

Adrenalectomy and nephrectomy

Died 18 months after surgery

Present case

2009

58

F

Left

16 cm × 11 cm

Asthenia, anorexia, weight loss, left abdominal mass and anemia

Adrenalectomy, nephrectomy and splenectomy

Local recurrence, alive 10 years after first surgery

Summary statistics

 

50.4 ± 17.2

Median = 49

M = 50.0%

Left = 58.3%

10.9 cm ± 3.8 cm

Median = 10 cm

Range = 6 cm to 17 cm