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Table 1 Reported cases of primary malignant melanoma of the adrenal gland

From: Primary melanoma of the adrenal gland: a case report and review of the literature

Reference Year Age Sex Location Size Clinical data Treatment Follow-up
Kniseley and Baggentoss [1] 1946 60 M Left 8.5 cm × 4.5 cm × 4.5 cm Back pain, abdominal mass, anorexia Radiotherapy Died two months after detection
Dick et al. [2] 1955 62 M Right 17 cm × 12 cm × 10 cm Painless, slowly growing mass Surgery without specification Died 15 months later
Sasidharan et al. [3] 1977 52 F Left 13 cm × 10 cm × 5 cm Asymptomatic; Well-defined, partly mobile, non-tender, globular lump confined to the left lumbar region Adrenalectomy and nephrectomy No follow-up
Carstens et al. [4] 1984 32 F Left 14 cm × 9 cm × 5 cm Pain in the left flank, weight loss Adrenalectomy and nephrectomy Died seven months later
Parker and Vincent [5] 1986 77 M Right   Asymptomatic. Casual finding in prostatic patient. Extrinsic compression of the proximal right ureter and displacement of the collecting system and renal contour laterally. Autopsy examination Died two months after diagnosis
Dao et al. [6] 1990 46 F Right 8 cm × 7 cm × 6 cm Severe right flank pain Adrenalectomy and nephrectomy Died one month later
Amérigo et al. [7] 2000 24 F Left 9 cm Intense post-prandial epigastric pain and weight loss Adrenalectomy and nephrectomy Alive 46 months later
Zalatnai et al. [8] 2003 41 F Left 7.3 cm × 6 cm Nausea, mild weight loss, abdominal tenderness and constant left flank pain Explorative laparotomy (non-resectable tumor) Died three months later
Granero et al. [9] 2004 78 M Right 11 cm Right flank pain, fever, nausea and vomiting Adrenalectomy, nephrectomy and splenectomy Alive 12 months later
Liatsikos et al. [10] 2006 42 M Left 5.5 cm × 6 cm Mild flank pain, weight loss and anemia Laparoscopic trans-peritoneal adrenalectomy Alive 12 months later
Bastide et al. [11] 2006 33 M Right - Right paroxystic lumbar pain, mass in the right flank Adrenalectomy and nephrectomy Died 18 months after surgery
Present case 2009 58 F Left 16 cm × 11 cm Asthenia, anorexia, weight loss, left abdominal mass and anemia Adrenalectomy, nephrectomy and splenectomy Local recurrence, alive 10 years after first surgery
Summary statistics   50.4 ± 17.2 Median = 49 M = 50.0% Left = 58.3% 10.9 cm ± 3.8 cm Median = 10 cm Range = 6 cm to 17 cm