Treatment of ovarian cancer ascites by intra-peritoneal injection of diphtheria toxin A chain-H19 vector: a case report

Table 1 Ovarian cancer compassionate patient treatments summary.

Treatment number	Plasmid infused (mg)	Time between treatments	AEs*
1-3	80	One week	2 hours after 1st treatment: vomiting once, fever 38.3°c for 3 hours, chill, weakness. 2nd & 3rd treatments: Nausea, vomiting once
4	108	One week	Nausea
5-6	120	One week	Nausea
7	140	One week	Nausea
8-10	120	Two weeks	No AEs

*During or immediately after plasmid instillation, patient received medications to control the fever elevation, nausea and vomiting.

ISSN: 1752-1947