Table 1 A summary of reported cases of gallbladder carcinoma with ovarian metastasis.
Author | No. of cases | Age (yrs) | Clinical presentation | Detection of primary/secondary | Laterality | Size (cm) | Histopathology of ovary | |
|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Â | Â | Â | Gross | Micro |
Khunamornpong et al.[2] | 8 | 47-83 | Pelvic mass, abdominal distension, vaginal bleeding, hematochezia n = 1 each abdominal pain, unknown n = 2 each | Primary first n = 3 Simultaneous n = 5 | Bilateral | 0.5-16.5 | Smooth external surface in majority, cut surface predominantly solid-cystic or solid in some, cyst content mucoid in majority | All except 1 were recognized as metastatic tumors; initially diagnosis was not appreciated in 1 case. All had foci indistinguishable from primary surface epithelial neoplasms |
Young and Scully[3] | 5 | 33-72 | Abdominal pain n = 4 Pelvic mass n = 1 | Primary first n = 1 Simultaneous n = 3 Ovarian first n = 1 | Bilateral | 2.5-13 | Lobulated external surface. Cut surface in all except 1 was nodular and solid | Half of them were difficult to diagnose and simulated primary ovarian neoplasm |
Ayhan et al.[4] | 1 | 33 | Abdominal pain | Simultaneous | Unilateral | 3 | - | - |
Miyagui et al.[5] | 1 | 43 | Confusion | Simultaneous | Bilateral | 17 and 19 | Cut surface compact intermingled with cystic areas containing yellow gelatinous fluid | Ovarian architecture entirely replaced neoplastic cells disposed in alveolar and trabecular patterns. Mucin & signet ring cells |
Jain et al.[6] | 1 | 45 | Pelvic mass | Simultaneous | Bilateral | - | - | Malignant cystic deposits |
Jarvi et al.[7] | 1 | 82 | Abdominal pain | Simultaneous | Bilateral | - | Solid cystic masses with focally roughened surfaces | Bilateral benign serous cystadenoma with deposits of metastatic adenocarcinoma |
Taranto et al.[8] | 1 | 52 | Pelvic mass | Primary first | Bilateral | 15 | - | Difficult to distinguish from a primary mucinous adenocarcinoma of the ovary even on histology |
Majumdar et al.[9] | 1 | 38 | Abdominal pain and distension | Simultaneous | Bilateral | 13 and 8 | - | Papillary pattern, cystic spaces, extracellular mucin, surface implants |
Kumar et al. (present study) | 2 | 35 62 | Abdominal pain Abdominal pain and distension | Simultaneous | Bilateral | 17 and 18 20 and 18 | Case 1: Solid cystic masses and gangrenous gallbladder Case 2: Entirely cystic, multiloculated ovarian masses filled with thick and thin mucin | Nodular growth with infiltrative pattern. Presence of surface deposits, cellular atypia, and infiltrative pattern |