Skip to main content

Table 1 Previously anti-retroviral naïve cases of HIV-GBS treated with HAART

From: Human immunodeficiency virus seroconversion presenting with acute inflammatory demyelinating polyneuropathy: a case report

Background/Demographics

Initial Treatment

Subsequent Progress

Reference

Age/Sex

GBS subtype

CD4 (cells/mm3)

IVIg given#

Mechanical Ventilation

First line HAART

 

Bani-Sadr et al 2002 [9]

35/M

AIDP

149

Not stated

No

ZDV/3TC/IDV/RTV

Complete recovery, HAART continued

Gisslén et al 2005[6]

35/M

AIDP

914

No

No

d4T/3TC/SQV/NLF

Improvement at 3/12 & HAART stopped. GBS recurred 2/12 later. IVIg & 5/12 more HAART (same regimen). No further recurrence when HAART discontinued

De Castro et al 2006 [10]

38/M

AIDP

502

Yes

Yes

ZDV/3TC/IDV

Complete recovery on long-term HAART. 2 transient GBS recurrences during HAART interruption for unrelated toxicity; 1. Renal lithiasis at 18/12; IDV→RTV 2.GI upset at 31/12; wkly IVIg for 6/12 RTV→EFV

Wagner et al 2007 [11]

46/M

AMAN

150

No

No

Regimen not stated

Complete recovery, HAART continued

Hiraga et al 2007 [4]

56/M

Fisher/GBS overlap+

24

Yes

No

Regimen not stated

Complete recovery, HAART continued

Sloan et al 2008 [this paper]

30/M

AIDP

408

Yes

No

ZVD/3TC/EFV

Complete recovery, HAART stopped at 6/12

  1. AZT: zidovudine, 3TC: lamivudine, IDV: indinavir, RTV: ritonavir, d4T: stavudine, SQV: saquinavir, NLF: nelfinavir, EFV: efavirenz.
  2. # IVIg dose: 0.4mg/kg IV daily for 5 days
  3. + Patient also treated for CSF & Cryptococcal Antigen positive Cryptococcus Neoformans meningitis