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  1. Delayed post-hypoxic leukoencephalopathy is a rare entity following hypoxia. Clinical and radiological signs of delayed post-hypoxic leukoencephalopathy have not previously been reported following acute ischem...

    Authors: Johannes A. R. Pfaff, Lukas Machegger, Eugen Trinka and Johannes Sebastian Mutzenbach
    Citation: Journal of Medical Case Reports 2022 16:480
  2. Bladder paraganglioma is a neuroendocrine tumor that accounts for less than 0.1% of all bladder tumors. Symptoms caused by catecholamine release such as hypertension, palpitation, syncope, and macroscopic hema...

    Authors: Tugay Aksakallı, Bakytbek Kozubaev, Turgut Yapanoğlu, Adem Utlu, Fatih Alper, Arzu Bilen and Numan Bulut
    Citation: Journal of Medical Case Reports 2022 16:479
  3. Ovarian steroid cell tumors, not otherwise specified is a rare sex cord-stromal tumor. Almost 60% of all steroid cell tumors are categorized as not otherwise specified and represent less than 0.1% of all ovari...

    Authors: Miry Lobaton-Ginsberg, Luz María Malanco-Hernández and Aldo Ferreira-Hermosillo
    Citation: Journal of Medical Case Reports 2022 16:478
  4. Multiple myeloma is a clonal plasma cell proliferation often causing bone lytic lesions. It is sometimes challenging to differentiate these lytic lesions associated with multiple myeloma from bone destruction ...

    Authors: Marwa Aloui, Sarra Ben Rejeb, Manel Boudokhan, Amen Dhaoui, Majdi Ben Romdhane and Syrine Belakhal
    Citation: Journal of Medical Case Reports 2022 16:477
  5. Paratesticular rhabdomyosarcoma is a rare and aggressive mesenchymal tumor, accounting for only 7% of all rhabdomyosarcomas. It is mainly encountered in children and adolescents. The standard treatment consist...

    Authors: Takoua Chalouati, Montassar Ghalleb, Amani Jallali, Maher Slimane, Ghada Sahraoui, Jamal Ben hassouna, Riadh Chargui and Khaled Rahal
    Citation: Journal of Medical Case Reports 2022 16:476
  6. The risk of developing severe and even fatal coronavirus disease 2019 (COVID-19) increases with various factors such as advanced age and chronic diseases, especially those treated with immunosuppressive drugs....

    Authors: Liba Sokolovska, Anna Terentjeva-Decuka, Maksims Cistjakovs, Zaiga Nora-Krukle, Sabine Gravelsina, Anda Vilmane, Katrine Vecvagare and Modra Murovska
    Citation: Journal of Medical Case Reports 2022 16:484
  7. Cushing’s syndrome consists of signs and symptoms related to prolonged exposure to high levels of glucocorticoid, and should be considered in individuals with the discriminatory signs and symptoms. Proximal my...

    Authors: Marjan Jeddi and Mesbah Shams
    Citation: Journal of Medical Case Reports 2022 16:483
  8. Invasive pulmonary Aspergillus and invasive bronchial aspergillosis is a life-threatening opportunistic fungal infection that predominantly affects immunocompromised hosts. A case series and review found that the...

    Authors: Shuku Sato, Wataru Kamata, Kiyomitsu Fukaguchi, Shun Tsunoda, Tadashi Kamio, Hiroshi Koyama, Hideyasu Sugimoto and Yotaro Tamai
    Citation: Journal of Medical Case Reports 2022 16:470
  9. Leiomyosarcoma is a rare malignant tumor of smooth muscle origin and represents 10–20% of all soft tissue sarcomas. Primary colon and rectal sarcomas constitute < 0.1% of all large bowel malignancies. In Li–Fr...

    Authors: Natalia Parisi Severino, Jaques Waisberg, Maria Candida Barisson Villares Fragoso, Luiz Guilherme Cernaglia Aureliano de Lima, Flavia Balsamo, Alexandre Cruz Henriques, Bianca Bianco and Flávia de Sousa Gehrke
    Citation: Journal of Medical Case Reports 2022 16:468
  10. Accessory breast carcinomas of the axilla of males are rare, and primary breast neuroendocrine tumors (BNETs) are rare as well. We present a case of a BNET arising in the axilla of a man.

    Authors: Kosei Kimura, Shigeru Kawabata, Hiroyo Oku, Ayana Ikari, Tomo Tominaga, Saki Takai, Junna Sakane, Michiaki Tanaka, Chinatsu Aoki, Monika Ota, Erika Minami, Yoshinobu Hirose, Sang-Woong Lee and Mitsuhiko Iwamoto
    Citation: Journal of Medical Case Reports 2022 16:467
  11. Ophthalmic manifestations are common in patients with leukemia, developing in nearly 50% of cases. Intracranial hemorrhage is another potentially fatal complication of leukemia. In this case report, we aim to ...

    Authors: MohammadJavad Ghanbarnia, Sadegh Sedaghat and Seyed Ahmad Rasoulinejad
    Citation: Journal of Medical Case Reports 2022 16:466
  12. Patients with underlying cardiovascular risk factors have worse clinical outcomes when they have coronavirus disease. In addition, a reduced workload of cardiovascular emergencies has been reported during the ...

    Authors: David O. Alao, Amani Alabdouli and Ala Jalabi
    Citation: Journal of Medical Case Reports 2022 16:475
  13. Polymyalgia rheumatica and giant cell arteritis are systemic inflammatory conditions of the elderly. Polymyalgia rheumatica classically presents as a bilateral proximal muscle pain and stiffness syndrome. Bice...

    Authors: Liyana Arachchige Dona Thulini Madubashini, Jayawardane Pathiranage Roneesha Lakmali and Nilanka Perera
    Citation: Journal of Medical Case Reports 2022 16:474
  14. Zoledronic acid is an intravenous, highly potent aminobisphosphonate for use in patients with primary or secondary osteoporosis. Zoledronic acid-induced prolonged side-effects are well known and quite common. ...

    Authors: Ilona Nurmi-Lüthje and Peter Lüthje
    Citation: Journal of Medical Case Reports 2022 16:473
  15. Felty syndrome is defined by three conditions: neutropenia, rheumatoid arthritis, and splenomegaly. Neutropenia associated with pancytopenia may further affect the dental condition of a patient. Periodontal tr...

    Authors: Satoru Morikawa, Yoko Miyashita, Mana Nasu, Shunichi Shibazaki, Satoshi Usuda, Kazuyuki Tsunoda and Taneaki Nakagawa
    Citation: Journal of Medical Case Reports 2022 16:463
  16. Multiple lumbar punctures have historically been a strategy to relieve headaches associated with idiopathic intracranial hypertension despite limited clinical evidence of long-term efficacy. Lumbar puncture is...

    Authors: Hannah S. Lyons, Satheesh Ramalingam, James L. Mitchell, Andreas Yiangou, Mark Thaller, Alexandra J. Sinclair and Susan P. Mollan
    Citation: Journal of Medical Case Reports 2022 16:464
  17. Adjuvant systemic therapy decreases recurrence and death from breast cancer, but late relapse still occurs. Therapeutic decisions are based heavily on receptor tissue characterization. Even though the vast maj...

    Authors: Yolcar Chamorro, Ana C. Sandoval-Leon, Charles L. Vogel, Michaela T. Nguyen and Grace Wang
    Citation: Journal of Medical Case Reports 2022 16:461
  18. Celiac disease is an immune-mediated enteropathy triggered by gluten in genetically susceptible individuals. Diagnosis is based on evaluating specific autoantibodies and histopathologic findings of duodenal bi...

    Authors: Barbora Packova, Pavel Kohout, Milan Dastych, Jitka Prokesova, Tomas Grolich and Radek Kroupa
    Citation: Journal of Medical Case Reports 2022 16:460
  19. Multiple myeloma remains incurable despite treatment advancements over the last 20 years. LCAR-B38M Cells in Treating Relapsed/Refractory Multiple Myeloma was a phase 1, first-in-human, investigator-initiated ...

    Authors: Bai-Yan Wang, Wan-Hong Zhao, Yin-Xia Chen, Xing-Mei Cao, Yun Yang, Yi-Lin Zhang, Fang-Xia Wang, Peng-Yu Zhang, Bo Lei, Liu-Fang Gu, Jian-Li Wang, Ju Bai, Yan Xu, Xu-Geng Wang, Rui-Li Zhang, Li-Li Wei…
    Citation: Journal of Medical Case Reports 2022 16:459
  20. The synovial chondromatosis is an uncommon proliferative metaplastic process of the synovial cells that can develop in any synovial joint. An isolated primary chondromatosis of the posterior compartment of the...

    Authors: Luigi Zanna, Gregorio Secci, Matteo Innocenti, Niccolò Giabbani, Roberto Civinini and Fabrizio Matassi
    Citation: Journal of Medical Case Reports 2022 16:457
  21. Strongyloidiasis is a soil-transmitted helminthiasis mainly caused by Strongyloides stercoralis. It is endemic to the tropics and subtropics. Sri Lanka has a 0–1.6% prevalence rate. S. stercoralis infection was i...

    Authors: Rumala Morel, Kusala Maddumabandara, Nisansala Amarasinghe, Sujeewa Amarangani, Anjalie Amarasinghe, Mihiri Gunathilaka, Gayani Wathsala, Lakmalee Bandara, Sunil Wijesundara, Nilupuli Gunaratne, Roshitha Waduge and Arjuna Medagama
    Citation: Journal of Medical Case Reports 2022 16:458
  22. Immune checkpoint inhibition with anti-PD(L)1 and anti-CTLA4 antibodies has significantly changed cancer treatment during the last 10 years. Nevertheless, boosting the immune system with immune checkpoint inhi...

    Authors: Sylvain Raoul Simeni Njonnou, Sandrine Aspeslagh, Marie-Josiane Ntsama Essomba, Marie-Lucie Racu, Fernando Kemta Lekpa and Frédéric Vandergheynst
    Citation: Journal of Medical Case Reports 2022 16:456
  23. Since the development of the coronavirus disease 2019 vaccine, there have been many reports of its adverse effects. While respiratory symptoms are common, many other symptoms in various organs have been report...

    Authors: Kyohei Tsuda, Akio Oishi and Takashi Kitaoka
    Citation: Journal of Medical Case Reports 2022 16:462
  24. Iatrogenic Cushing’s syndrome induced by oral and parenteral glucocorticoid administration is a well-known complication. Immediate withdrawal from exogenous steroids can lead to life-threatening adrenal insuff...

    Authors: Nicola Matejek, Johannes Hoos, Paul Martin Holterhus, Markus Bettendorf and Daniela Choukair
    Citation: Journal of Medical Case Reports 2022 16:455
  25. Myositis ossificans circumscripta is a self-limiting, benign, ossifying lesion that can affect any type of soft tissue. It is most commonly found in muscles as a solitary lesion. A history of recent trauma has...

    Authors: Pierre-Yves Cren, Nicolas Penel, Abel Cordoba, Gauthier Decanter, Louise Gaboriau and Mariem Ben Haj Amor
    Citation: Journal of Medical Case Reports 2022 16:454
  26. Coronavirus disease 2019 can lead to rare but severe and life-threatening diseases in susceptible high-risk populations, including patients with immunodeficiency. A rare event in this report is stroke followi...

    Authors: Hanie Karimi, Roham Sarmadian, Abolfazl Gilani, Poorya salajegheh, Habibe Nejad Biglari and Mahsa Gholizadeh
    Citation: Journal of Medical Case Reports 2022 16:452
  27. Iatrogenic left main coronary artery dissection is a rare but serious complication that can occur both during diagnostic coronary angiography and percutaneous coronary intervention. Early diagnosis and choice ...

    Authors: Charalampos Varlamos, Efthymia Varytimiadi, Despoina-Rafailia Benetou and Dimitrios Alexopoulos
    Citation: Journal of Medical Case Reports 2022 16:469
  28. Authors: Christian J. Fludder and Braden G. Keil
    Citation: Journal of Medical Case Reports 2022 16:451

    The Letter to the Editor to this article has been published in Journal of Medical Case Reports 2022 16:453

    The original article was published in Journal of Medical Case Reports 2022 16:20

  29. Cases of large bowel closed-loop phenomenon with cecal perforation are extremely rare, especially when extracolonic epiploic appendage and peritoneal bands are the cause. However, sporadic cases exist in the l...

    Authors: Mohamed Eltayeb Abdelrahman Naiem and Suliman Hussein Suliman
    Citation: Journal of Medical Case Reports 2022 16:450
  30. The Mycobacterium abscessus complex is a nontuberculous mycobacteria species that is pervasive in soil and water. Various medical equipment malfunctions, infected surfaces, and patient transmission are potential ...

    Authors: Karam R. Motawea, Randa K. Rabea, Rowan H. Elhalag, Jason Goodloe, Dina M. Awad, Manmeet Kaur, Ahmed K. Awad, Sarya Swed and Joseph Varney
    Citation: Journal of Medical Case Reports 2022 16:448
  31. Methotrexate is an antifolate antimetabolite that inhibits the activity of dihydrofolate reductase by acting as a false substrate, which leads to defects of DNA synthesis, specifically the inhibition of purine...

    Authors: Sareena Shah, Kristen Haeger-Overstreet and Brigid Flynn
    Citation: Journal of Medical Case Reports 2022 16:447
  32. Aneurysmal bone cysts are benign bone tumors that not uncommonly involves the spine. However, this involvement can cause scoliosis, albeit rarely. This report focuses on the importance of proper management for...

    Authors: Yousef M. Aljamaan, Hisham S. Alhathloul, Sami I. Aleissa, Majid S. Abaalkhail, Fahad H. Alhelal and Faisal M. Konbaz
    Citation: Journal of Medical Case Reports 2022 16:446
  33. Primary treatment of central neurocytomas is surgical resection. Gamma Knife surgery is considered a valuable therapeutic option in case of residual (after subtotal resection) or recurrent central neurocytomas...

    Authors: Michaela Dedeciusova, John O. Prior, Luis Schiappacasse, David Patin, Marc Levivier and Constantin Tuleasca
    Citation: Journal of Medical Case Reports 2022 16:441
  34. Umbilical discharge in an adult is rare and generates broad diagnostic considerations. Umbilical anatomy is variable owing to congenital abnormalities and acquired pathology such as umbilical hernias. The umbi...

    Authors: Yong-hun Kim, Abigail K. Wegehaupt and Majken T. Wingo
    Citation: Journal of Medical Case Reports 2022 16:444
  35. Ectopic breast tissue is present in 2–6% of women. Ectopic mammary tissue can experience physiological changes and the same pathological processes as the eutopic breast. Ectopic breast cancer represents an unc...

    Authors: Leila Achouri, Amani Jellali, Houda Henchiri, Sabrine Boukhris, Yosra Zaaimi, Houyem Mansouri and Najet Mahjoub
    Citation: Journal of Medical Case Reports 2022 16:443
  36. Given the current climate of the pandemic, lung cancer patients are especially vulnerable to complications from severe acute respiratory syndrome coronavirus 2 infection. As a high-risk population group, these...

    Authors: Shreya Tripathy, Nathaniel Alvarez, Shubham Jaiswal, Ryan Williams, Munaf Al-Khadimi, Sarah Hackman, William Phillips, Supreet Kaur, Sherri Cervantez, William Kelly and Josephine Taverna
    Citation: Journal of Medical Case Reports 2022 16:445
  37. Vascular involvement is an infrequent clinical manifestation of Behçet’s syndrome. Owing to the rarity of arterial involvement in Behçet’s syndrome, there is limited experience in managing this phenomenon.

    Authors: Hamed Ghoddusi Johari, Seyed Arman Moein, Saeedeh Shenavande, Armin Amirian and Sara Sadat Nabavizadeh
    Citation: Journal of Medical Case Reports 2022 16:439
  38. In recent years, the number of patients with ischemic skin ulcers due to diabetes mellitus and arteriosclerosis obliterans are increasing. Accordingly, endovascular therapy, drugs, and various wound dressings ...

    Authors: Masakatsu Hihara, Michika Fukui, Toshihito Mitsui, Natsuko Kakudo and Atsuyuki Kuro
    Citation: Journal of Medical Case Reports 2022 16:434
  39. Acute dacryocystitis is an atypical and rare manifestation of pediatric mononucleosis still widely underdiagnosed in clinical practice. We report this rare condition and describe challenges in its diagnosis an...

    Authors: J. Sternberg, S. Lambiel, H. Cao Van, H. Massa and B. N. Landis
    Citation: Journal of Medical Case Reports 2022 16:430
  40. Attention deficit/hyperactivity disorder (ADHD) entails inattention, impulsivity, and restlessness at a disabling level. The pharmacological treatment of ADHD rests on the use of centrally acting stimulants, s...

    Authors: Ane Rogne and Bjørnar Hassel
    Citation: Journal of Medical Case Reports 2022 16:425
  41. Aerococcus urinae is a bacterium of emerging clinical interest that most commonly causes urinary tract infections (UTI) but can also result in invasive infections. It is a catalase-negative, alpha-haemolytic gram...

    Authors: Chong Wei Tiong, Caroline Bartolo, Aaron Walton and Eugene Athan
    Citation: Journal of Medical Case Reports 2022 16:438
  42. Gadolinium-based contrast agents are used extensively in magnetic resonance imaging to assist diagnosis of medical conditions. Despite their documented safety profile, severe adverse events do occur, and their...

    Authors: Eduardo Atsushi Osawa, Juliana Fernandez Fernandes Kleiman and Alexandre Toledo Maciel
    Citation: Journal of Medical Case Reports 2022 16:421

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