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  1. Flexion contracture in the lower extremity is a common finding in the patient with neuromusculoskeletal disorders. However, severe cases due to prolonged immobilization in knee–chest position are rarely establ...

    Authors: Ahmad Jabir Rahyussalim, Muhammad Luqman Labib Zufar and Tri Kurniwati
    Citation: Journal of Medical Case Reports 2022 16:225
  2. Women with female genital mutilation/cutting are known to have psychological sequelae from the cutting and other traumatic experiences. However, very few studies report immediate psychological sequelae of geni...

    Authors: Gianmarco Taraschi, Emily Manin, Francesco Bianchi De Micheli and Jasmine Abdulcadir
    Citation: Journal of Medical Case Reports 2022 16:223
  3. Adrenocorticotropic hormone therapy for infantile spasms, including West syndrome, has been previously reported to induce seizures. We present the findings for a school-aged child with epilepsy who developed n...

    Authors: Yoshitaka Ota, Shuichi Shimakawa, Hikaru Tsuda-Kitahara, Miho Fukui, Mitsuru Kashiwagi and Akira Ashida
    Citation: Journal of Medical Case Reports 2022 16:200
  4. Bilateral ureteropelvic junction obstruction is a common cause of secondary hypertension in the pediatric population, often due to congenital malformation. On the other hand, it is less frequently encountered ...

    Authors: Bruce Adrian Casipit, Jerald Pelayo, Joseph Alexander Paguio, Jasper Seth Yao and Niel Shah
    Citation: Journal of Medical Case Reports 2022 16:220
  5. Pyoderma gangrenosum and cutaneous squamous cell carcinoma are two conditions well reported in the literature and may exist concurrently in the same patient. In fact, there have been reports of misdiagnosis of...

    Authors: Amy Morrison, Carlene Waters-Hollingsworth and G. Mabel Gamboa
    Citation: Journal of Medical Case Reports 2022 16:199
  6. Bullet embolus is a rare condition following gunshot injuries and represents a clinical challenge regarding both diagnosis and management.

    Authors: Ahmad Hosseinzadeh, Mohammad Moeini Farsani, Mohamad Mahdi Mahmoudi, Ahmadreza Hekmatnia, Meghdad Ghasemi Gorji, Majid Asnaashari, Hamed Ghoddusi Johari and Reza Shahriarirad
    Citation: Journal of Medical Case Reports 2022 16:198
  7. P wave morphology on electrocardiogram is often overlooked but indicates abnormal cardiac conduction from various etiologies. Split P waves on electrocardiogram have been reported previously but not in a perio...

    Authors: Marianne C. Chen and Jay B. Brodsky
    Citation: Journal of Medical Case Reports 2022 16:197
  8. The spread of cervical squamous cell carcinoma to the inner surface of the uterus with replacement of the endometrium is rare. Continuity of the lesion must be demonstrated to confirm superficial spread and ru...

    Authors: Javier Martín-Vallejo, Juan B. Laforga, Patricia Molina-Bellido and Pedro A. Clemente-Pérez
    Citation: Journal of Medical Case Reports 2022 16:196
  9. Sarcoidosis is a benign systemic granulomatous disorder of unknown etiology. Cell-mediated immunity disorder is often found in sarcoidosis patients, and an association between malignant tumors and sarcoidosis ...

    Authors: Yuka Oride, Yumiko Koi, Tatsunari Sasada, Keiko Kajitani, Masahiro Ohara, Tomohiro Kondo, Yutaka Daimaru and Shingo Kawamura
    Citation: Journal of Medical Case Reports 2022 16:194
  10. Primary psoas tuberculosis is the presence of “Koch’s bacillus’’ within the iliopsoas muscle caused by hematogenous or lymphatic seeding from a distant site. Muscular tuberculosis has relatively low prevalence...

    Authors: Abdul Fattah Mohandes, Bahjat Karam, Ali Alrstom, Lugien Alasadi, Mohammad wahid Rajab Bek, Nizar Daher, Tamim Alsuliman and Raed Abouhareb
    Citation: Journal of Medical Case Reports 2022 16:209
  11. Collecting duct carcinoma and sarcomatoid renal cell carcinoma are tumors with poor prognosis. Immune checkpoint inhibitors have been established as the standard treatment for advanced renal cell carcinoma. So...

    Authors: Takayoshi Fuu, Kazuyoshi Iijima, Yukiko Kusama, Toshiaki Otsuki and Haruaki Kato
    Citation: Journal of Medical Case Reports 2022 16:193
  12. Incidence of myocarditis following messenger RNA coronavirus disease 2019 vaccination has been widely described, but this clinical scenario after adenoviral vector coronavirus disease 2019 vaccination has only...

    Authors: Apichai Marsukjai, Nonthikorn Theerasuwipakorn, Monravee Tumkosit, Pairoj Chattranukulchai, Panudda Srichomkwun and Somchai Prechawat
    Citation: Journal of Medical Case Reports 2022 16:212
  13. Timely diagnosis of uterine torsion can lead to acceptable maternal and fetal outcomes. This article presents the case of a 42-year-old pregnant woman, diagnosed with a rare 270° uterine torsion, in whom prope...

    Authors: Seyedeh Noushin Ghalandarpoor-Attar and Seyedeh Mojgan Ghalandarpoor-Attar
    Citation: Journal of Medical Case Reports 2022 16:210
  14. Inadequate response to corneal laser refractive surgery, e.g., ectatic corneal diseases, may not be identified by conventional examinations, hence creating therapeutic uncertainty. Herein we demonstrate the ap...

    Authors: Andrea Cusumano, Hila Roshanravan, Connie Chao-Shern, Jacopo Sebastiani, Jung Hee Levialdi Ghiron, Larry DeDionisio and Tara Moore
    Citation: Journal of Medical Case Reports 2022 16:207
  15. Doppler transthoracic echocardiography is routinely performed to measure peak mitral inflow velocities in the assessment of left ventricular diastolic function. The limitations of echocardiography are well doc...

    Authors: Paul Njoku, James Wardley and Pankaj Garg
    Citation: Journal of Medical Case Reports 2022 16:205
  16. Ocular vascular occlusion is an extremely rare event, especially in the young population. This diagnosis is always associated with active systemic diseases in young adults and needs thrombophilia workup. Never...

    Authors: Mohammadreza Mehrabi Bahar, Seyedeh Noushin Ghalandarpoor-Attar, Azadeh Shabani, Sedigheh Hantoushzadeh, Seyed Ali Tabatabaei and Seyedeh Mojgan Ghalandarpoor-Attar
    Citation: Journal of Medical Case Reports 2022 16:191
  17. Acute puerperal uterine inversion is rare but may cause massive postpartum blood loss due to uterine atony. Therefore, these patients must be diagnosed, and uterine replacement must be performed as soon as pos...

    Authors: Wataru Isono, Akira Tsuchiya, Asuka Okamura, Michiko Honda, Ako Saito, Hiroko Tsuchiya, Reiko Matsuyama, Akihisa Fujimoto and Osamu Nishii
    Citation: Journal of Medical Case Reports 2022 16:190
  18. Gaucher disease is an autosomal recessive inborn error of metabolism that causes disorders of blood, bone, and central nervous system as well as hepatosplenomegaly. We present the case of a carrier of Gaucher ...

    Authors: Takako Sugiura, Arisa Fujiwara, Takasugi Yo, Kana Kashinoura, Chihiro Hayase, Yumiko Taura, Yasuhiro Kawarabayashi, Yasuyuki Hasuo and Shinji Ogawa
    Citation: Journal of Medical Case Reports 2022 16:203
  19. Rhododendron toxicity can be a life-threatening situation when manifested; it results in bradycardia and hypotension. Treatment remains challenging when it is complicated with refractory hypotension involving ...

    Authors: Sushil Baral, Binaya Kumar Baral, Pranit Sharma and Surendra Lal Shrestha
    Citation: Journal of Medical Case Reports 2022 16:189
  20. Elongation of the styloid process associated with oropharyngeal pain and dysphagia is known as Eagle’s syndrome, a condition whose pathophysiology is still a matter of debate. Given its low prevalence and comp...

    Authors: Yves Boucher, Agatha Mularski, Rufino Felizardo, Frédéric Tankere and Marc Dieb
    Citation: Journal of Medical Case Reports 2022 16:201
  21. Respiratory and gastrointestinal manifestations are the main causes of mortality and morbidity in cystic fibrosis. Although these symptoms are well recognized, ophthalmic involvement of cystic fibrosis seconda...

    Authors: Nazanin Farahbakhsh, Neda Bagherian, Sajad Shabanpourhaghighi, Soheila Khalilzadeh, Seyed Ahmad Tabatabaii and Ghamartaj Khanbabaee
    Citation: Journal of Medical Case Reports 2022 16:188
  22. Mutations or polymorphisms of genes that are associated with inflammasome functions are known to predispose individuals to Crohn’s disease and likely affect clinical presentations and responses to therapeutic ...

    Authors: Harumi Jyonouchi and Lee Geng
    Citation: Journal of Medical Case Reports 2022 16:187
  23. Teprotumumab is a novel treatment that reduces inflammation and symptoms caused by thyroid eye disease. There are limited data on teprotumumab’s effect on intraocular pressure.

    Authors: Matthew Chu, Jonathan Sung, Michael Song, Alice Song and Julia Song
    Citation: Journal of Medical Case Reports 2022 16:195
  24. Fungal prosthetic graft infections are associated with high mortality, typically requiring aggressive surgical debridement. We present an alternative, minimally invasive approach to address these challenging c...

    Authors: Ashley T Giammarino, Iam Claire Sarmiento, SJacob Scheinerman, John Winalski, Richard S Lazzaro, Derek R Brinster and Jonathan M Hemli
    Citation: Journal of Medical Case Reports 2022 16:186
  25. Elderly and frail patients who are unable to call for help in case of vital distress can develop complications during their hospitalization. As a supplement to clinical monitoring by the nursing staff, these p...

    Authors: Daniel Aiham Ghazali, Philippe Kenway, Christophe Choquet and Enrique Casalino
    Citation: Journal of Medical Case Reports 2022 16:185
  26. Despite some advances, treatment of trigeminal neuralgia remains a significant challenge. This study determines the efficacy and safety of autologous conditioned serum (Orthokine) injection into the foramen ov...

    Authors: Dawood Aghamohammadi, Shahrzad Sharifi, Seyed Kazem Shakouri, Yashar Eslampour and Neda Dolatkhah
    Citation: Journal of Medical Case Reports 2022 16:183
  27. Many scientists across the world got involved in the race to develop successful anti-SARS-CoV-2 vaccines to overcome COVID-19 pandemic. Among the different vaccines developed against SARS-CoV-2, Covishield was...

    Authors: Mukesh Kumar Sah, Bishnu Mohan Singh, Puja Sinha, Prerit Devkota, Sudhira Kumari Yadav, John Shrestha and Ashis Shrestha
    Citation: Journal of Medical Case Reports 2022 16:182

    The Correction to this article has been published in Journal of Medical Case Reports 2022 16:266

  28. Cystinosis is an autosomal recessive disorder characterized by an accumulation of the amino acid cystine in lysosomes throughout the body. Cystinosis is an inherited disease resulting from the failure of lysos...

    Authors: Sepideh Gholami Yarahmadi, Fatemeh Sarlaki and Saeid Morovvati
    Citation: Journal of Medical Case Reports 2022 16:181
  29. Bullous pemphigoid is an uncommon dermatologic manifestation seen in squamous cell lung cancer, and evidence guiding optimal treatment, especially in the elderly population, is limited. We report herein a case...

    Authors: Prajwol Shrestha, Mathew K. George, Sweta Baidya and Sunil K. Rai
    Citation: Journal of Medical Case Reports 2022 16:184
  30. Mutations in the genes encoding the large-conductance calcium-activated potassium channel, especially KCNMA1 encoding its α-subunit, have been linked to several neurological features, including intellectual disab...

    Authors: Olivier Perche, Fabien Lesne, Alain Patat, Susanne Raab, Roy Twyman, Robert H. Ring and Sylvain Briault
    Citation: Journal of Medical Case Reports 2022 16:180
  31. The present case contributes to the limited literature on delayed chest wall hematomas following blunt trauma. The literature review provides a summary of similar previously reported cases.

    Authors: Anna Maria Florescu, Ane Brøndum Lange, Erik Gudmann Steuble Brandt, Anders Vestergaard Krusenstjerna-Hafstrøm, Henrik Vad and Peter Hallas
    Citation: Journal of Medical Case Reports 2022 16:179
  32. Acquired hemophilia A is a disorder caused by autoantibodies against coagulation factor VIII that may present with severe bleeding. We report a rare case of acquired hemophilia A presenting with coexisting lup...

    Authors: Victor Chen, Lauren C. Roby, Stephanie Wentzel, Mingjia Li and Nicholas Jones
    Citation: Journal of Medical Case Reports 2022 16:177
  33. Among all ectopic pregnancies, between 0.5% and 3.5% are ovarian ectopic pregnancies, a potentially life-threatening condition when ruptured due to its serious potential for hemorrhaging. A majority of ovarian...

    Authors: Sara Kasraei, Akram Seifollahi, Faezeh Aghajani, Amin Nakhostin-Ansari, Neda Zarei and Afsaneh Tehranian
    Citation: Journal of Medical Case Reports 2022 16:175
  34. Neurofibromatosis type 1 is an inherited cancer predisposition syndrome that is caused by a mutation in the NF1 gene that encodes neurofibromin. Patients with neurofibromatosis type 1 have a higher risk of gastro...

    Authors: B. G. Bharath, Sameer Rastogi, Shamim Ahmed and Adarsh Barwad
    Citation: Journal of Medical Case Reports 2022 16:174
  35. Managing treatment-resistant aggressive giant prolactinoma can be challenging, as the diagnosis is often complex, and treatment beyond dopamine agonists, surgery, and radiotherapy is limited.

    Authors: Marisa Khatijah Borhan and Florence Hui Sieng Tan
    Citation: Journal of Medical Case Reports 2022 16:170
  36. It is very important to determine the indication of mold radiotherapy for the radical treatment of oral cancer. We investigated eight patients with oral squamous cell carcinoma who were treated by radical irra...

    Authors: Tadahide Noguchi, Yasushi Sugiura, Akihiro Dohi, Manabu Yamada, Naruo Okada, Ken-ichi Sasaguri, Satoru Takahashi and Yoshiyuki Mori
    Citation: Journal of Medical Case Reports 2022 16:178
  37. Bardet–Biedl syndrome is a rare multisystem autosomal recessive disorder that falls under the spectrum of ciliopathy disorders. It is characterized by rod–cone dystrophy, renal malformations, polydactyly, lear...

    Authors: Omer Ali Mohamed Ahmed Elawad, Mumen Abdalazim Dafallah, Mohammed Mahgoub Mirghani Ahmed, Ahmed Abdalazim Dafallah Albashir, Sahar Mohammed Abbas Abdalla, Habiballa Hago Mohamed Yousif, Anwar Ali Elamin Daw Elbait, Moawia Elbalal Mohammed, Hassan Ismail Hassan Ali, Mohamed Mutasim Mohamed Ahmed, Najla Fouad Nassir Mohammed, Fadwa Hashim Mohamed Osman, Mussab Alnazeer Yousif Mohammed and Ejlal Ahmed Ebrahim Abu Shama
    Citation: Journal of Medical Case Reports 2022 16:169
  38. Mandible can be the site of benign or malignant lesions of different origins, including odontogenic and non-odontogenic lesions. Cartilage-forming tumors have been rarely reported at this site. Chondrosarcoma ...

    Authors: Ayman Ismail, Imane Boujguenna, Koussay Hattab, Nadia Mansouri, Najat Cherif Idrissi El Ganouni, Mariem Ouali Idrissi, Fatima Ezzahra Hazmiri and Hanane Rais
    Citation: Journal of Medical Case Reports 2022 16:176
  39. The most common complication of pelvic organ prolapse is stress urinary incontinence, whereas hydronephrosis or stasis ulcers are quite rare and typical of severe stages. The best treatment for this unusual pr...

    Authors: Vito Leanza, Alessandra Di Stefano, Erika Carlotta Paladino, Luca Rivoli, Rosario Emanuele Carlo Distefano and Marco Palumbo
    Citation: Journal of Medical Case Reports 2022 16:173
  40. This review highlights the rising prevalence of methamphetamine use in pregnancy in North American and the difficulty of managing active human immunodeficiency virus infection in a pregnant woman while activel...

    Authors: Suzanne Turner, Maya Nader and Erin Lurie
    Citation: Journal of Medical Case Reports 2022 16:165
  41. Our patient presents with a novel presentation of a fungated ulcerated skin lesion as the initial presentation of lung cancer. The literature describes skin metastases from lung cancer as nodular, papular, and...

    Authors: Rose Chisenga, Tasneem Adenwala, William Kim, Daniel Mujuni and Rachel Samuel
    Citation: Journal of Medical Case Reports 2022 16:172
  42. Giant ovarian tumors are rarely seen with severe obesity. There are few reports of perioperative management of giant ovarian tumors and severe obesity. Here, we report the perioperative management of physiolog...

    Authors: Shoko Yamochi, Mao Kinoshita and Teiji Sawa
    Citation: Journal of Medical Case Reports 2022 16:164
  43. Capecitabine is widely used in chemotherapy for breast, colorectal, and gastric cancers. The frequent adverse reactions of capecitabine mainly include gastrointestinal side effects, anemia, and cardiovascular ...

    Authors: Qiaoling Yang, Chuping Chen and Jianmin Ran
    Citation: Journal of Medical Case Reports 2022 16:163
  44. We describe the outcome of ultra-low-dose radiotherapy plus intravitreal methotrexate and rituximab injections for a patient with primary choroidal lymphoma who presented with nodular conjunctival salmon patch...

    Authors: Zahra Mahdizad, Elias Khalili Pour, Mohammadreza Mehrabi Bahar, Amirreza Esfandiari, Babak Masoomian, Hamid Riazi-Esfahani, Ahmad Mirshahi and Fariba Ghassemi
    Citation: Journal of Medical Case Reports 2022 16:162
  45. Endometriomas are a type of ovarian cyst composed of degenerated blood products from hemorrhage of ectopic endometrial tissue. Endometriomas can rupture, causing hemoperitoneum, and present with signs and symp...

    Authors: Hayley Young, Thanh-Lan Bui, Scott E. Cramer, Ryan O’Connell and Roozbeh Houshyar
    Citation: Journal of Medical Case Reports 2022 16:161
  46. The coronavirus disease 2019 syndrome typically consists of respiratory symptoms and other general nonspecific symptoms. Psychotic manifestations of coronavirus disease 2019 attributable to severe acute respir...

    Authors: Nyanyuie Kodjo Lovi, Selase Kofi Kekrebesi, Mary Osei and Eugene Yeboah
    Citation: Journal of Medical Case Reports 2022 16:171
  47. Renal adenomatosis is a rare disease that presents as multiple papillary adenomas in the bilateral kidneys. Moreover, papillary adenoma is considered a precursor to papillary renal cell carcinoma. Therefore, p...

    Authors: Yi-Chen Chou, Wen-Ying Lee, Steven K. Huang, Reng-Hong Wu and Yu-Ting Kuo
    Citation: Journal of Medical Case Reports 2022 16:168
  48. Cardiac tumors in infants and children are rare. The most common cardiac tumor is rhabdomyoma, which may be associated with tuberous sclerosis. However, not all cardiac rhabdomyomas are pathognomonic for tuber...

    Authors: Mohammed Alsabri, Alejandro Gonzalez, Aaron Sircy, Sai Sarada Policherla and Kemi Mascoll-Robertson
    Citation: Journal of Medical Case Reports 2022 16:166
  49. Salbutamol is a selective β2-receptor agonist widely used to treat asthma in both emergency and outpatient settings. However, it has been associated with a broad spectrum of side effects. Lactic acidosis and d...

    Authors: Marco Colombo, Anna Plebani, Annalisa Bosco and Massimo Agosti
    Citation: Journal of Medical Case Reports 2022 16:160

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