Articles

Graves’ disease coexisted with resistance to thyroid hormone: a case report

Resistance to thyroid hormone is a rare autosomal dominant disorder characterized by reduced responsiveness to thyroid hormone and can cause syndrome of inappropriate secretion of thyroid stimulating hormone. ...

Authors: Hiroshi Akahori and Rika Usuda

Concomitant familial hypocalciuric hypercalcemia and single parathyroid adenoma: a case report

Primary hyperparathyroidism (PHPT) is a common endocrine disorder and the most frequent benign cause of hypercalcemia. PHPT is characterized by autonomous hypersecretion of parathyroid hormone (PTH), regardles...

Authors: Simone Diedrichsen Marstrand, Charlotte Landbo Tofteng, Anne Jarløv, Line Borgwardt and Peter Schwarz

Correction to: Avascular femoral necrosis as part of Cushing syndrome presentation: a case report

Authors: Daniela Salazar, César Esteves, Maria João Ferreira, Jorge Pedro, Tiago Pimenta, Raquel Portugal and Davide Carvalho

Tubulointerstitial nephritis and uveitis syndrome following meningitis and systemic lymphadenopathy with persistent Toxoplasma immunoglobulin M: a case report

Tubulointerstitial nephritis and uveitis syndrome is a rare lymphocyte-related oculorenal inflammatory disease presumed to be associated with drug use and infectious agents. Toxoplasma gondii is one of such patho...

Authors: Yoshihiro Oya, Hidekazu Futami, Takuya Nakazawa, Kazuyuki Ishijima, Keiko Umemiya, Fumiyoshi Takizawa, Naoki Imai, Hiroshi Kitamura and Ryutaro Matsumura

First case of childhood Takayasu arteritis from Syria: a case report

Takayasu arteritis is a systemic granulomatous inflammation affecting the large- and medium-sized vessels such as aorta, its main branches, and pulmonary and renal arteries. Childhood Takayasu arteritis is a s...

Authors: Wafa Alwattar, Rawan Al khudari, Judy Naameh, Jia Batha, Raghad Almajzoub and Basheer Khalil

Unilateral Urrets-Zavalia syndrome after Implantable Collamer Lens implantation: a case report and review of the literature

Fixed dilated pupil after ophthalmic surgery or Urrets-Zavalia syndrome occurs after anterior segment surgery and usually relates to postoperative elevation of intraocular pressure. Urrets-Zavalia syndrome res...

Authors: Duangratn Niruthisard and Ngamjit Kasetsuwan

Sorafenib-related generalized eruptive keratoacanthomas (Grzybowski syndrome): a case report

Sorafenib is an oral multikinase inhibitor that targets Raf serine/threonine receptor tyrosine kinases and inhibits tumor cell growth and angiogenesis. Cutaneous toxicities of sorafenib are common, including ...

Authors: M. Nazim Abbas, Wei Son Tan and Ganessan Kichenadasse

Scrotal wall leiomyosarcoma: a case report and review of the literature

Up to 30% of all scrotal masses are sarcomas. Leiomyosarcoma of the scrotal wall is rare, and its clinical significance and prognosis have not been well defined, since the most reported cases have little or no...

Authors: Zahra Erfani, Aileen Azari-yam and Seyed Reza Yahyazadeh

Megaloblastic anemia-related iron overload and erythroid regulators: a case report

In ineffective erythropoiesis, hepcidin synthesis is suppressed by erythroid regulators, namely erythroferrone and growth differentiation factor-15. For the first time, the hypothesis that iron overload in meg...

Authors: Nicolas Vallet, Jean-Baptiste Delaye, Martine Ropert, Amélie Foucault, Noémie Ravalet, Sophie Deriaz, Thomas Chalopin, Hélène Blasco, François Maillot, Olivier Hérault and Emmanuel Gyan

Severe sequelae in bilateral acute iris transillumination syndrome secondary to the use of oral moxifloxacin: a case report

Moxifloxacin is a fourth-generation fluoroquinolone used as a second-line treatment for multiple bacterial infections. Uveitis has been described as an adverse effect related to this medication. Although sever...

Authors: Nicolás Rivera-Valdivia, Karla Arteaga-Rivera, Juliana Reyes-Guanes, Natalia Neira-Segura and Alejandra de-la-Torre

Use of CytoSorb therapy to treat critically ill coronavirus disease 2019 patients: a case series

Acute respiratory distress syndrome is an important clinical presentation of respiratory complications caused by severe acute respiratory syndrome coronavirus 2, a novel coronavirus responsible for the ongoing...

Authors: Yatin Mehta, Chitra Mehta, Saurabh Nanda, Gaurav Kochar, Joby V. George and Manish Kumar Singh

Systemic lupus erythematous presenting with hemorrhagic shock caused by gastric penetration of pancreatic pseudocyst: a case report

Systemic lupus erythematous that causes various organ damage is rarely associated with pancreatic lesion. To the best of our knowledge, no cases presenting with hemorrhage shock caused by gastric penetration o...

Authors: Hideya Itagaki and Suzuki Katuhiko

Gonococcus infection probably acquired from bathing in a natural thermal pool: a case report

Authorities need to recognize that, while rare, gonorrhea can be transmitted nonsexually, and should not be presumed definitive evidence of abuse. We report the unusual case of a girl diagnosed with Neisseria gon...

Authors: Felicity Goodyear-Smith and Robert Schabetsberger

Isolated pancreatic injury in an adolescent treated with Roux-en-Y pancreatojejunostomy: a case report and review of the literature

Pancreatic injury presented as isolated injury in the pediatric population is exceptionally rare, with a conveyed incidence of less than 2% of all abdominal trauma injuries cases and a very controversial manag...

Authors: Mohamed Eltayeb Abdelrahman Naiem and Nassir Alhaboob Arabi

Sporadic intra-abdominal desmoid tumor with a very unusual onset: two case reports

Intra-abdominal desmoid tumors are rare soft tissue tumors that arise mainly in the mesentery and pelvis. Their etiology may include genetic mutations, estrogen-associated changes after childbirth, and mechani...

Authors: Hiroshi Kuwabara, Sou Katayanagi, Itsuki Koganezawa, Masashi Nakagawa, Kenji Katsumata, Akihiko Tsuchida and Shigeyuki Kawachi

Advanced-stage Wilms tumor arising in a horseshoe kidney of a 9-year-old child: a case report

Horseshoe kidney (HK) is one of the most common renal fusion abnormalities, with an incidence of 1:400 in the normal population. However, Wilms tumor (WT) arising in an HK is a rare occurrence. We report the c...

Authors: Abubakar Garba Farouk, H. A. Ibrahim, A. Farate, S. Wabada and M. G. Mustapha

Acute respiratory distress syndrome caused by carbon monoxide poisoning and inhalation injury recovered after extracorporeal membrane oxygenation along with direct hemoperfusion with polymyxin B-immobilized fiber column: a case report

Inhalation injury from smoke or chemical products and carbon monoxide poisoning are major causes of death in burn patients from fire accidents. Respiratory tract injuries from inhalation injury and carbon mono...

Authors: Ji Hoon Jang, Hang Jea Jang, Hyun-Kuk Kim, Jin Han Park, Hyo-Jung Kim, Kyeong Min Jo, Woon Heo, Se Hun Kim, Tae-Hoon No and Jae Ha Lee

Secondary cluster headache and numb chin syndrome as initial manifestation of high-grade B-lymphoma: a case report

Cluster headache is a primary condition characterized by severe headache accompanied by trigeminal autonomic signs. By definition, it is not attributed to underlying etiologies; however, under certain clinical...

Authors: Joe Munoz-Cerón, Felipe Díaz-Forero, Adriana Buitrago and Sandra Chinchilla

Late presentation of a cauda equina lesion with a vulval abscess: a case report

Cauda equina syndrome is a rare clinical condition that requires prompt diagnosis and timely surgical decompression with postoperative rehabilitation to prevent devastating complications.

Authors: Chanil Deshan Ekanayake, Deepal Weerasekera, Dilini Dissanayake, Ranga Wickramarachchi, Saman Pushpakumara and Dumitha Govindapala

Critical iron deficiency anemia with record low hemoglobin: a case report

Anemia is a serious global health problem that affects individuals of all ages but particularly women of reproductive age. Iron deficiency anemia is one of the most common causes of anemia seen in women, with ...

Authors: Audrey L. Chai, Owen Y. Huang, Rastko Rakočević and Peter Chung

Coronavirus disease 2019 outcomes in heart transplant recipients: a single-center case series

With the rapidly expanding pandemic of severe acute respiratory syndrome coronavirus-2, a chronic immunosuppressed state in solid organ transplant recipients is a concern. We reported coronavirus disease 2019 ...

Authors: Farah Naghashzadeh, Shadi Shafaghi, Babak Sharif-Kashani, Payam Tabarsi, Leila Saliminejad and Sima Noorali

Migrated fish bone into the neck: a case report

Impaction of foreign body is a common condition presented to ear, nose, and throat department among Asian population. The commonest foreign body seen among this population has been documented as fish bone. Fis...

Authors: Vasanthika Sanjeewanie Thuduvage

Extremely high troponin levels induced by septic shock: a case report

Troponin levels can be elevated in various diseases other than acute myocardial infarction, including sepsis. In diseases without myocardial necrosis, the elevated troponin levels are relatively low and normal...

Authors: Naoki Matsunaga, Yuki Yoshioka and Yasushi Fukuta

Coinfection with dengue and hepatitis A complicated with infective endocarditis in a Yemeni patient: a case report

Coinfection with dengue and hepatitis A is rare and challenging for physicians since their clinical features can be overlapping. These infections are self-limiting but can become complicated by subsequent infe...

Authors: Shafiq A. Alemad, Abdulsalam M. Halboup, Khaled Aladeeb, Mohamed Al-Saleh and Nuha Al-Kufiley

Surgical navigation system for temporomandibular joint ankylosis in a child: a case report

Computer-assisted surgical navigation systems were initially introduced for use in neurosurgery and have been applied in craniomaxillofacial surgery for 20 years. The anatomy of the oral and maxillofacial regi...

Authors: Ryo Miyazaki, Akinori Iwasaki, Fumi Nakai and Minoru Miyake

Unclogging the effects of the Angiojet® thrombectomy system on kidney function: a case report

AngioJet® is an increasingly used method of percutaneous mechanical thrombectomy for the treatment of patients with arterial and venous thromboses. AngioJet® has been shown to cause intravascular haemoylsis un...

Authors: Tayeba Roper, Muhammad Amaran, Prakash Saha, Cormac Breen and David Game

Acute pancreatitis associated with severe acute respiratory syndrome coronavirus-2 infection: a case report and review of the literature

We report a case of Severe acute respiratory syndrome coronavirus-2 infection with acute pancreatitis as the only presenting symptom. To the best of our knowledge, there are few case reports of the same presen...

Authors: Abdullah S. Eldaly, Ayman R. Fath, Sarah M. Mashaly and Muhammed Elhadi

Shift of musical hallucinations to visual hallucinations after correction of the hearing deficit in a patient with Lewy body dementia: a case report

Musical hallucinations are a particular type of auditory hallucination in which the patient perceives instrumental music, musical sounds, or songs. Musical hallucinations are associated with acquired hearing l...

Authors: Alexandre Montalvo, Eryco Azevedo and Alexandre de Mendonça

Placenta increta presenting with threatened miscarriage during the first trimester in rhesus-negative mother: a case report

Placenta accreta is known to be associated with significant maternal morbidity and mortality—primarily due to intractable bleeding during abortion or delivery at any level of gestation. The complications could...

Authors: Nik Lah Nik-Ahmad-Zuky, Azmel Seoparjoo and Engku Ismail Engku Husna

A neonate with Klippel–Trénaunay syndrome: a case report 

Klippel–Trénaunay syndrome is a rare congenital capillary–lymphatic–venous condition characterized by the clinical triad of capillary malformations (port wine stains), varicose veins with or without venous mal...

Authors: Franck Katembo Sikakulya, Walufu Ivan Egesa, Sonye Magugu Kiyaka and Philip Anyama

Late reinfection with a different severe acute respiratory syndrome coronavirus-2 clade in a patient with refractory arterial hypertension: a case report

Differentiating between persistent infection with intermittent viral shedding and reinfection with severe acute respiratory syndrome coronavirus 2 remains challenging. Although a small number of cases with gen...

Authors: Javier García-Abellán, Antonio Galiana, Marta Fernández-González, Nieves Gonzalo-Jiménez, Montserrat Ruiz-García, Angela Botella, Joan Sanchis, Paula Mascarell, Selene Falcón, Mar Masiá and Félix Gutiérrez

Phlegmonous gastritis: a case series

Phlegmonous gastritis is a rare and fatal infectious disease of the stomach, presenting varied and nonspecific endoscopic images, which are therefore difficult to diagnose. This report discusses three cases of...

Authors: Yoshikazu Yakami, Toshihiko Yagyu and Tomoki Bando

Immunoglobulin G4 hypophysitis in a 63-year-old woman with no autoimmune history: a case report

Immunoglobulin-G4-related hypophysitis is a rare inflammatory disease that can present as a tumefactive pituitary lesion mimicking hypophyseal neoplasms such as pituitary adenoma or craniopharyngioma. The lite...

Authors: Zachary C. Gersey, Kenan R. Rajjoub, Thomas M. Pearce, Scott A. Segel, Paul A. Gardner, Carl H. Snyderman, Eric W. Wang and Georgios A. Zenonos

Tubulointerstitial nephritis and uveitis syndrome in an adolescent female: a case report

Tubulointerstitial nephritis with uveitis syndrome is a rare disease affecting mainly children and young women. Tubulointerstitial nephritis with uveitis is a diagnosis of exclusion, requiring a high degree of...

Authors: Tadej Petek, Maja Frelih and Nataša Marčun Varda

Takotsubo cardiomyopathy in elderly female trauma patients: a case series

Takotsubo cardiomyopathy is a syndrome characterized by acute left ventricular wall motion abnormalities leading to left ventricular systolic dysfunction. It remains an important differential diagnosis for acu...

Authors: Vishal Patel, Shuli Levy, Iqbal Malik, Michael B. Fertleman and Louis J. Koizia

Spontaneous massive hemothorax as a complication of necrotizing pneumonia in a patient with severe acute respiratory syndrome coronavirus 2 induced acute respiratory distress syndrome: a case report

We present an unusual bleeding complication in a patient with severe acute respiratory distress syndrome in coronavirus disease 2019.

Authors: Carolin Jung, Hans-Joerg Gillmann, Thomas Stueber and Lukas Hinken

Intrathecal baclofen therapy for severe spasticity in an adult with tethered cord syndrome: a case report

Patients with tethered cord syndrome often suffer severe spasticity. To the best of our knowledge, intrathecal baclofen (ITB) therapy in a patient with tethered cord syndrome has not been reported previously. ...

Authors: Yasutaka Takagi, Hiroshi Yamada, Hidehumi Ebara, Hiroyuki Hayashi, Satoshi Kidani, Kazu Toyooka, Yuji Ishino, Yoshiyuki Kitano, Aki Nakanami, Kenji Kagechika, Tetsutaro Yahata and Hiroyuki Tsuchiya

A novel mutation in ACADVL causing very long-chain acyl-coenzyme-A dehydrogenase deficiency in a South Asian pediatric patient: a case report and review of the literature

Very long-chain acyl-coenzyme-A dehydrogenase deficiency is a rare, severe life-threatening metabolic disorder of mitochondrial fatty acid oxidation, caused by mutations in ACADVL gene. Here we present a genetica...

Authors: Visvalingam Arunath, Manoj Sanjeewa Liyanarachchi, Sundararajah Gajealan, Eresha Jasinge, Kumudu Weerasekara and Lia Abbasi Moheb

Atypical idiopathic intracranial hypertension presenting as cyclic vomiting syndrome: a case report

Idiopathic intracranial hypertension is a disorder of increased intracranial pressure in the absence of cerebrospinal outflow obstruction, mass lesion, or other underlying cause. It is a rare phenomenon in pre...

Authors: Nafee T. Talukder, Amanda H. Clorfeine, Moira K. Black and Shade B. Moody

Challenges of dengue and coronavirus disease 2019 coinfection: two case reports

Dengue fever and coronavirus disease 2019 have now begun to overlap within tropical and subtropical regions. This is due to the high prevalence of dengue fever in these regions and the current severe acute res...

Authors: Olga Lucia Agudelo Rojas, María Elena Tello-Cajiao and Fernando Rosso

Spindle cell squamous cell carcinoma exhibiting prominent neutrophil phagocytosis: a case report

Spindle cell squamous cell carcinoma is an uncommon variant of squamous cell carcinoma; its diagnosis is sometimes challenging because it histopathologically resembles neoplastic or reactive spindle cell lesio...

Authors: Manabu Yamazaki, Satoshi Maruyama, Tatsuya Abé, Yoshimasa Sumita, Yuji Katsumi, Yutaka Nikkuni, Takafumi Hayashi and Jun-ichi Tanuma

Xeroderma pigmentosum and acute myeloid leukemia: a case report 

Xeroderma pigmentosum is a rare inherited disease characterized by extreme hypersensitivity to ultraviolet rays and predisposing to cutaneous malignancies that can appear in childhood. These manifestations are...

Authors: H. Bencharef, M. Lamchahab, D. Dassouli, S. Sraidi, B. Guennoun, N. Hda, B. Oukkache and A. Quessar

Multiple schwannomas of the facial nerve mimicking cervical lymphoma: a case report

In this report, we describe the first case in literature of a patient with multiple schwannomas of the marginal mandibular branch of the facial nerve.

Authors: Jan Philipp Kühn, Mathias Wagner, Alessandro Bozzato and Maximilian Linxweiler

Acute pharmacogenetic dystonic reactions in a family with the CYP2D6 *41 allele: a case report

Dystonia is a known neurological complication of certain medications; however, the mechanism behind such effects is often undetermined. Similarly, the clinical pharmacogenomic effects associated with various a...

Authors: Darice Y. Wong and Brent L. Fogel

Beta-lactamase-negative ampicillin-resistant Haemophilus influenzae type b meningitis in partially immunized immunocompetent child: a case report

Haemophilus influenzae is a Gram-negative coccobacillus that can cause many different kinds of infection, ranging from mild ear infection to life-threatening diseases like epiglottitis and meningitis. Encapsulate...

Authors: Majid Ali Qureshi, Imran Asad, Adeel Chaudhary and Walid Abuhammour

Primary diffuse large B-cell lymphoma of the cranial vault with Trousseau syndrome: a case report

It is extremely rare for primary non-Hodgkin’s lymphomas to occur singly in the cranial vault. One case diagnosed as primary diffuse large B-cell lymphoma is reported, initially misdiagnosed as metastatic skul...

Authors: Tatsuya Uchida, Kenichi Amagasaki, Atsushi Hosono and Hiroshi Nakaguchi

Humeral metastasis as the only recurrence of a 5-year resected gastrointestinal stromal tumor: a case report

Gastrointestinal stromal tumors represent the most frequently encountered primary mesenchymal tumors. Whereas the liver and the peritoneum are known to be the preferential metastasis sites, no therapeutic stan...

Authors: C. Braunstein, F. Sirveaux, E. Kalbacher, S. Aubry, D. Delroeux, P. Hubert, B. Marie, G. Meynard, I. Mihai and L. Chaigneau

An assessment of esophageal balloon use for the titration of airway pressure release ventilation and controlled mechanical ventilation in a patient with extrapulmonary acute respiratory distress syndrome: a case report

Esophageal pressure measurement is a minimally invasive monitoring process that assesses respiratory mechanics in patients with acute respiratory distress syndrome. Airway pressure release ventilation is a rel...

Authors: Óscar Arellano-Pérez, Felipe Castillo Merino, Roberto Torres-Tejeiro and Sebastián Ugarte Ubiergo

Multiple site neural tube defects at Zewuditu Memorial Hospital, Addis Ababa, Ethiopia: a case report

Neural tube defects are common group of central nervous system anomalies of complex etiology and major public health importance worldwide. The occurrence of multiple neural tube defects, however, is an extreme...

Authors: Mestet Yibeltal Shiferaw, Atalel Fentahun Awedew, Tsegazeab Laeke T/Mariam, Abenezer Tirsit Aklilu, Yemisirach Bizuneh Akililu and Aemiro Mazengia Andualem

Young adult with Gorham’s disease presenting in an emergency department: a case report

Gorham’s disease is a very rare musculoskeletal disorder characterized by progressive resorption of one or more skeletal bones. Most of the 200 cases reported earlier are diagnosed before the age of 40 years. ...

Authors: Markku Grönroos and Ari Palomäki