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  1. Primary treatment of central neurocytomas is surgical resection. Gamma Knife surgery is considered a valuable therapeutic option in case of residual (after subtotal resection) or recurrent central neurocytomas...

    Authors: Michaela Dedeciusova, John O. Prior, Luis Schiappacasse, David Patin, Marc Levivier and Constantin Tuleasca
    Citation: Journal of Medical Case Reports 2022 16:441
  2. Umbilical discharge in an adult is rare and generates broad diagnostic considerations. Umbilical anatomy is variable owing to congenital abnormalities and acquired pathology such as umbilical hernias. The umbi...

    Authors: Yong-hun Kim, Abigail K. Wegehaupt and Majken T. Wingo
    Citation: Journal of Medical Case Reports 2022 16:444
  3. Ectopic breast tissue is present in 2–6% of women. Ectopic mammary tissue can experience physiological changes and the same pathological processes as the eutopic breast. Ectopic breast cancer represents an unc...

    Authors: Leila Achouri, Amani Jellali, Houda Henchiri, Sabrine Boukhris, Yosra Zaaimi, Houyem Mansouri and Najet Mahjoub
    Citation: Journal of Medical Case Reports 2022 16:443
  4. Given the current climate of the pandemic, lung cancer patients are especially vulnerable to complications from severe acute respiratory syndrome coronavirus 2 infection. As a high-risk population group, these...

    Authors: Shreya Tripathy, Nathaniel Alvarez, Shubham Jaiswal, Ryan Williams, Munaf Al-Khadimi, Sarah Hackman, William Phillips, Supreet Kaur, Sherri Cervantez, William Kelly and Josephine Taverna
    Citation: Journal of Medical Case Reports 2022 16:445
  5. Vascular involvement is an infrequent clinical manifestation of Behçet’s syndrome. Owing to the rarity of arterial involvement in Behçet’s syndrome, there is limited experience in managing this phenomenon.

    Authors: Hamed Ghoddusi Johari, Seyed Arman Moein, Saeedeh Shenavande, Armin Amirian and Sara Sadat Nabavizadeh
    Citation: Journal of Medical Case Reports 2022 16:439
  6. In recent years, the number of patients with ischemic skin ulcers due to diabetes mellitus and arteriosclerosis obliterans are increasing. Accordingly, endovascular therapy, drugs, and various wound dressings ...

    Authors: Masakatsu Hihara, Michika Fukui, Toshihito Mitsui, Natsuko Kakudo and Atsuyuki Kuro
    Citation: Journal of Medical Case Reports 2022 16:434
  7. Acute dacryocystitis is an atypical and rare manifestation of pediatric mononucleosis still widely underdiagnosed in clinical practice. We report this rare condition and describe challenges in its diagnosis an...

    Authors: J. Sternberg, S. Lambiel, H. Cao Van, H. Massa and B. N. Landis
    Citation: Journal of Medical Case Reports 2022 16:430
  8. Attention deficit/hyperactivity disorder (ADHD) entails inattention, impulsivity, and restlessness at a disabling level. The pharmacological treatment of ADHD rests on the use of centrally acting stimulants, s...

    Authors: Ane Rogne and Bjørnar Hassel
    Citation: Journal of Medical Case Reports 2022 16:425
  9. Aerococcus urinae is a bacterium of emerging clinical interest that most commonly causes urinary tract infections (UTI) but can also result in invasive infections. It is a catalase-negative, alpha-haemolytic gram...

    Authors: Chong Wei Tiong, Caroline Bartolo, Aaron Walton and Eugene Athan
    Citation: Journal of Medical Case Reports 2022 16:438
  10. Gadolinium-based contrast agents are used extensively in magnetic resonance imaging to assist diagnosis of medical conditions. Despite their documented safety profile, severe adverse events do occur, and their...

    Authors: Eduardo Atsushi Osawa, Juliana Fernandez Fernandes Kleiman and Alexandre Toledo Maciel
    Citation: Journal of Medical Case Reports 2022 16:421
  11. Miller-Fisher Syndrome (MFS) is a variant of Guillain–Barré syndrome (GBS), an acute immune-mediated neuropathy, which manifests as a rapidly evolving areflex motor paralysis. This syndrome presents as a class...

    Authors: Fernanda Junqueira Cesar Pirola, Bruno Antônio Müzel Santos, Gabriela Feres Sapienza, Lucas Yuri Cetrangolo, Caio Henrique Wthen Gambacorta Geranutti and Paulo Henrique Pires de Aguiar
    Citation: Journal of Medical Case Reports 2022 16:437
  12. The supra-acetabulum is a common site for malignant bone tumors, which can be difficult to differentiate from insufficiency fractures. We report a rare case of a stress fracture of the supra-acetabulum that re...

    Authors: Sei Morinaga, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Hirotaka Yonezawa, Yohei Asano, Shiro Saito and Hiroyuki Tsuchiya
    Citation: Journal of Medical Case Reports 2022 16:436
  13. Desmoid tumors are extremely rare borderline benign and malignant tumors that do not exhibit accumulation on fluorodeoxyglucose positron emission tomography–computed tomography. In the present study, we report...

    Authors: Kento Kawashima, Kazuhiro Hiramatsu, Takehito Kato, Masahide Fukaya, Taro Aoba, Atsuki Arimoto and Takayuki Yamaguchi
    Citation: Journal of Medical Case Reports 2022 16:423
  14. Spinal muscular atrophy is a recessively inherited autosomal neuromuscular disorder, with characteristic progressive muscle weakness. Most spinal muscular atrophy cases clinically manifest during infancy or ch...

    Authors: Cempaka Thursina Srie Setyaningrum, Indra Sari Kusuma Harahap, Dian Kesumapramudya Nurputra, Mawaddah Ar Rochmah, Ahmad Hamim Sadewa, Giga Hasabi Alkarani and Nur Imma Fatimah Harahap
    Citation: Journal of Medical Case Reports 2022 16:435
  15. Ewing sarcoma is a malignant bone tumor; however, its prognosis has improved since the development of modern chemotherapy. Although Ewing sarcoma outcomes have improved, issues related to late complications, s...

    Authors: Ryota Hagihara, Hidetaka Arishima, Takahiro Yamauchi, Satoshi Kawajiri, Tomomi Ito, Mana Fukushima and Kenichiro Kikuta
    Citation: Journal of Medical Case Reports 2022 16:419
  16. Gastric mixed neuroendocrine–non-neuroendocrine neoplasms are rare malignant tumors. The lack of specific findings makes it difficult to diagnose endoscopically. We report the case of early gastric mixed neuro...

    Authors: Yohei Ito, Yoshiaki Kimoto, Rikimaru Sawada, Shinya Nagae, Koichi Furuta, Nao Takeuchi, Shunya Takayanagi, Yuki Kano, Rindo Ishii, Takashi Sakuno, Kohei Ono, Ryoju Negishi, Yohei Minato, Takashi Muramoto and Ken Ohata
    Citation: Journal of Medical Case Reports 2022 16:416
  17. There are few reports of trigger wrist in the literature, as it is a rare pathology. Furthermore, various authors report that it is also hard to diagnose. It manifests with neurological symptoms at the affecte...

    Authors: Alexey V. Lychagin, Dmitry S. Bobrov, Kirill D. Artemov, Yaroslav A. Rukin, Vadim G. Cherepanov, Ekaterina E. Rudenko and Andrey B. Ponomarev
    Citation: Journal of Medical Case Reports 2022 16:415
  18. The Hypotension Prediction Index (HPI) displays an innovative monitoring tool which predicts intraoperative hypotension before its onset.

    Authors: Sara Denn, Emmanuel Schneck, Fidaa Jablawi, Michael Bender, Götz Schmidt, Marit Habicher, Eberhard Uhl and Michael Sander
    Citation: Journal of Medical Case Reports 2022 16:412
  19. May–Thurner syndrome is a vascular disorder caused by the right common iliac artery compressing the left common iliac vein against the lumbar spine, causing distal venous stasis and potentially leading to fibr...

    Authors: Kevin D. Seely, Heidi J. Arreola, Loveleen K. Paul, Jordan A. Higgs, Benjamin Brooks and Randal C. Anderson
    Citation: Journal of Medical Case Reports 2022 16:411
  20. A congenital band is an uncommon abnormality that can be found anywhere along the gastrointestinal tract. Intestinal obstruction caused by an anomalous congenital band is very rare in children. To the best of ...

    Authors: Gulan Maree, Ali Alelayan, Ferhad Hemi, Waseem Shater, Alaa Ghuzlan and Wajih Ali
    Citation: Journal of Medical Case Reports 2022 16:433
  21. Diagnosis of venous aneurysm may be difficult and can be misjudged as mass-like lesions, including hernias. Here we present the case of a patient with a great saphenous vein aneurysm misdiagnosed and operated ...

    Authors: Hamed Ghoddusi Johari, Hamidreza Malekhosseini, Amirhossein Erfani and Reza Shahriarirad
    Citation: Journal of Medical Case Reports 2022 16:410
  22. Coronavirus disease 2019 has changed the pattern of some diseases in the world, especially in pediatrics. Despite data suggesting that the pediatric population is less affected by coronavirus disease-19 infect...

    Authors: Mohammad Hasan Aelami, Abdolreza Malek and Amin Saeidinia
    Citation: Journal of Medical Case Reports 2022 16:432
  23. Anti-leucine-rich glioma-inactivated 1 encephalitis is a newly emerged entity characterized by frequent faciobrachial dystonic seizures and a wide spectrum of subacute clinical symptoms such as other seizure t...

    Authors: Sanaz Ahmadi Karvigh, Saeideh Salehizadeh and Fahimeh Vahabizad
    Citation: Journal of Medical Case Reports 2022 16:409
  24. Abacavir is a nucleoside reverse transcriptase inhibitor that is used as a component of the antiretroviral treatment regimen in the management of the human immunodeficiency virus for both adults and children. ...

    Authors: Mathew K. Koech, Shamim M. Ali, Mercy J. Karoney and Gabriel Kigen
    Citation: Journal of Medical Case Reports 2022 16:407
  25. Opportunistic infections are frequent in people living with the human immunodeficiency virus who either do not have access to antiretroviral therapy (ART) or use it irregularly. Tuberculosis is the most freque...

    Authors: Gleiciere Maia Silva, Bruna Rodrigues de Sousa, Kaliny Benicio Torres, Rejane Pereira Neves, Heloisa Ramos Lacerda de Melo and Reginaldo Gonçalves de Lima-Neto
    Citation: Journal of Medical Case Reports 2022 16:429
  26. Kaposi sarcoma is a vascular tumor highly related to human herpesvirus-8 and Kaposi sarcoma–associated herpesvirus. Kaposi sarcoma usually manifests as skin or mucosal lesions; involvement in visceral organs s...

    Authors: Pei-Jui Wu, Chi-Shu Sun, Hsing-Tao Kuo, Ming-Jen Sheu, Cheng-Yi Lin, Su-Hung Wang, Chun-Chi Yang, Chi‐Hsing Chen, Shih-Sung Chuang and I-Che Feng
    Citation: Journal of Medical Case Reports 2022 16:424
  27. Children with nephrotic syndrome are at increased risk of infections, including bacterial peritonitis, pneumonia, and cellulitis. However, bacterial meningitis, a potentially life-threatening complication, has...

    Authors: David Guernsey, Aparna Arun, Rabia Agha and Juan C. Kupferman
    Citation: Journal of Medical Case Reports 2022 16:403
  28. Most testicular tumors are germ cell tumors; sex cord stromal tumors are infrequent, accounting for only 3–5% of testicular tumors. Unclassified sex cord stromal tumors are extremely rare. Generally, 10% of se...

    Authors: Shingo Morinaga, Shigeyuki Aoki, Toyonori Tsuzuki, Keiko Kanematsu, Naoki Kawai, Sayuri Sato, Kotomi Nakamizu, Kana Goto, Miho Niwa, Ikuko Nomura, Tomoko Sawada, Ruriko Futamachi, Fujio Morita and Yoshiaki Yamada
    Citation: Journal of Medical Case Reports 2022 16:406
  29. There is ample evidence indicating that immunosuppressive therapy or immune dysregulation in systemic lupus erythematosus increases the risk for tuberculosis. Interestingly, a few case reports suggest that tub...

    Authors: Shekhar, Nikita Yogesh Gupta and Avi Ravi Harisingani
    Citation: Journal of Medical Case Reports 2022 16:428
  30. Tapia’s syndrome is a rare complication of airway manipulation under general anesthesia. Injuries to the vagus nerve (X) and hypoglossal nerve (XII) during transoral intubation are the primary cause of the dis...

    Authors: Luan Xie, Zhenyu Xiong, Weihong Xiao, Yingnan Mo, Xiangliang Li, Xuan Zhuang, Ying Yang and Haipeng Jin
    Citation: Journal of Medical Case Reports 2022 16:408
  31. Down’s syndrome is the most common chromosomal abnormality in humans. It has been associated with central nervous system tumors such as primary acute lymphoblastic leukemia and germinomas, but desmoplastic inf...

    Authors: Muhammad Hamza Habib, Mehvish Zahra Alavi, Amber Goraya, Samina Zaman and Alia Ahmed
    Citation: Journal of Medical Case Reports 2022 16:427
  32. Body stuffing and body packing are two methods of concealing illicit drugs. Body stuffing is defined as the oral ingestion of illicit drugs, typically to avoid law enforcement detection or other consequences o...

    Authors: Tegan Schmidt, Yuliya Matolina, Arianna S. Neeki, Caros Peace, Benjamin Archambeau, Fanglong Dong and Michael M. Neeki
    Citation: Journal of Medical Case Reports 2022 16:426
  33. There have hardly been any reported cases of children presenting with Kaposi sarcoma as a second malignancy following treatment for acute lymphoblastic leukemia outside a transplant setting.

    Authors: Richard Nyeko, Fadhil Geriga, Racheal Angom and Joyce Balagadde Kambugu
    Citation: Journal of Medical Case Reports 2022 16:405
  34. Recently, an unknown hepatitis outbreak among children has concerned many individuals worldwide. These cases are frequently reported, mainly from Europe and other countries. In this study, we present two simil...

    Authors: Ali Ghanei-Shahmirzadi, Hamid Reihani, Ali Abbasi-Kashkooli, Fereshteh Karbasian, Seyyed Bozorgmehr Hedayati, Mohammadreza Bordbar, Maryam Ataollahi, Seyed Mohsen Dehghani and Bita Geramizadeh
    Citation: Journal of Medical Case Reports 2022 16:422
  35. The advent of immunotherapies has ushered in a new era in the treatment of non-small cell lung carcinoma. Although immunotherapies are associated with improved clinical outcomes, studies report a median overal...

    Authors: Jeffrey Mathew Boby, Nurul Nadia Mohd Ghazali, Anita Mani and Mathew George
    Citation: Journal of Medical Case Reports 2022 16:420
  36. Human brucellosis is the most frequently contracted zoonotic infection worldwide. Although being an old disease that carries minimal risks of mortality, it remains a source of considerable sequelae and disabil...

    Authors: Sarah Gerges, Alessandro Khoury, Souheil Hallit, Fadi Hoyek and Rabih Hallit
    Citation: Journal of Medical Case Reports 2022 16:418
  37. Waldenström’s macroglobulinaemia is a rarely encountered B-lymphocytic malignancy. Waldenström’s macroglobulinaemia-associated paraproteinaemia is linked to an increase in serum viscosity, which results in a h...

    Authors: Raeed Deen, Calyb Austin, Alexander Bowden and Andrew Bullen
    Citation: Journal of Medical Case Reports 2022 16:417
  38. Psoriatic arthritis treatment with antitumor necrosis factor has been shown to reduce disease activity. Nonetheless, more than 30% of patients do not achieve a sufficient response to tumor necrosis factor bloc...

    Authors: Tatsuhiko Kutsuna, Kazunori Hino, Hitoshi Hasegawa, Kunihiko Watamori, Teruki Kidani, Hiroshi Imai and Hiromasa Miura
    Citation: Journal of Medical Case Reports 2022 16:402
  39. Lung involvement in inflammatory bowel diseases usually follows colitis. However, the time to lung involvement onset varies depending on the case, and pulmonary lesions are usually not parallel to exacerbation...

    Authors: Shouichi Okamoto, Kengo Koike, Mitsuaki Sekiya, Koichi Nishino, Tomoyasu Mimori and Kazuhisa Takahashi
    Citation: Journal of Medical Case Reports 2022 16:414
  40. We report a case of acute respiratory distress associated with a histological pattern of acute fibrinous and organizing pneumonia, and discuss the possible responsibility of flecainide therapy.

    Authors: Gauthier Moureau, Elies Zarrouk, Delphine Hoton, Franck Saint-Marcoux, Lidvine Boland, Vincent Haufroid and Philippe Hantson
    Citation: Journal of Medical Case Reports 2022 16:404
  41. A previously healthy young male of Southeast Asian descent presented with 6 weeks of fevers, cough, mucocutaneous ulcers, arthritis, and myalgias. Initial workup revealed positive Mycoplasma pneumoniae immunoglob...

    Authors: Jessica Hoey, Jenny Lue Solomon, Brandon Kim, Steven Carsons and Julie Nusbaum
    Citation: Journal of Medical Case Reports 2022 16:401
  42. Pfieffer syndrome is among the syndromes seen in the recognized variant of the FGFR2 gene. There are several conditions related to this variant and a very closely related condition is Crouzon syndrome. This ca...

    Authors: Karim P. Manji, Mariam Mngoya Massomo, Edna Samson Akyoo and McLean Abisai Luvinga
    Citation: Journal of Medical Case Reports 2022 16:399
  43. We report two similar cases of patients diagnosed with hemiballismus–hemichorea syndrome secondary to uncontrolled hyperglycemia. Both patients were treated at an inpatient rehabilitation center and made a sig...

    Authors: Luke Tsai, Benjamin Shekhtman, Ryan Stenquist, Ashley Schneider, Meilani Mapa, Edwin Amirianfar and David R. Gater
    Citation: Journal of Medical Case Reports 2022 16:398
  44. Lymphangiomas are rare benign malformations of the lymphatics that occur due to blockage of the lymphatic system during fetal development. They commonly occur in the neck and axilla, while involvement of the p...

    Authors: Hashan Pathiraja, Dhammike Rasnayake, Thilini Muthukumarana, Channa de Silva, Wasantha Sathkorala, Sandini Gunaratne, Shaman Rajindrajith and Sachith Mettananda
    Citation: Journal of Medical Case Reports 2022 16:397
  45. The use of checkpoint inhibitors has become increasingly important in the treatment of different cancers, including advanced muscle-invasive urothelial cancer and even in basal cell carcinoma. We present the c...

    Authors: Zsófia Küronya, Tímea Danyi, Tímea Balatoni, Gabriella Liszkay, Erika Tóth, Krisztina Biró and Lajos Géczi
    Citation: Journal of Medical Case Reports 2022 16:396

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