Skip to main content
Figure 1 | Journal of Medical Case Reports

Figure 1

From: Expression of tumor necrosis factor-alpha converting enzyme and matrix metalloproteinase-3 in proliferated synovium in a patient with synovitis-acne-pustulosis-hyperostosis-osteitis syndrome: a case report

Figure 1

Macro- and microscopic findings of synovitis-acne-pustulosis-hyperostosis-osteitis syndrome synovitis. Note that rheumatoid arthritis-like villous contoured synovial tissues with rich blood circulation are markedly proliferated (a). Continuous paraffin sections were stained with hematoxylin and eosin (b) or immunostained with antibodies against tumor necrosis factor-alpha converting enzyme (c, e), matrix metalloproteinase-3 (d, f), tumor necrosis factor-alpha (g), or CD68 (h). Note that hyperplastic synovitis with lymphoid nodules similar to rheumatoid arthritis (b), and tumor necrosis factor-alpha converting enzyme, tumor necrosis factor-alpha and matrix metalloproteinase-3 are expressed in synovial lining cells (c-g). Arrows, synovial lining cells. Scale bar, 100 μm.

Back to article page