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Table 1 Cases report of endometrial osseous metaplasia treated by hysteroscopy

From: Osseous metaplasia of the endometrium associated with infertility: a case report and review of the literature



Case description


Rodriguez BD, Adamson GD: Hysteroscopic treatment of ectopic intrauterine bone. A case report. J Reprod Med 1993, 38: 515-520. [4]

Patient with infertility had a diagnosis of endometrial osseous metaplasia, which was removed successfully by hysteroscopy assisted by laparoscopy. She delivered a healthy infant.


Marcus S, Bhattacharya J, Williams G, Brinsden P, Hamou J: Endometrial ossification: a case of secondary infertility. Report of two cases. Am J Obstet Gynecol 1994, 170: 1381-1383. [10]

Report of two cases of osseous metaplasia. One patient conceived spontaneously.


Bahceci M, Demirel LC: Osseous metaplasia of the endometrium: a rare cause of infertility and its hysteroscopic management. Hum Reprod 1996, 11: 2537–-2539. [20]

Case report of a patient with secondary infertility after an abortion 12 years previously. Two months after resection of the osseous lesion the patient conceived spontaneously.


Coccia ME, Becattini C, Bracco GL, Scarselli G: Ultrasound-guided hysteroscopic management of endometrial osseous metaplasia. Ultrasound Obstet Gynecol 1996, 8: 134-136. [19]

Case report of a patient with metrorrhagia and leucorrhea, with a previous normal delivery and a previous 25-week gestation loss. Osseous metaplasia was diagnosed by hysteroscopy and resected. Patient became asymptomatic after the procedure.


Torné A, Jou P, Pagano R, Sanchez I, Ordi J, Vanrell JA: Endometrial ossification successfully treated by hysteroscopic resection. Eur J Obstet Gynecol Reprod Biol 1996, 66: 75-77. [11]

Case report of a patient with dysmenorrhea, with two previous voluntary abortions and a diagnosis of endometrial osseous metaplasia, which was treated by hysteroscopic removal of the lesion, with complete resolution of symptoms.


García León F, Kably Ambe A: Osseous metaplasia of the endometrium as a cause of infertility. Hysteroscopic approach. Ginecol Obstet Mex 1999, 67: 37-41. [21]

Patient with infertility with hysteroscopic diagnosis of osseous metaplasia, which was resected surgically.


Van den Bosch T, Dubin M, Cornelis A: Favourable pregnancy outcome in a woman with osseous metaplasia of the uterus. Ultrasound Obstet Gynecol 2000, 15: 445-447. [22]

Patient with diagnosis of endometrial osseous metaplasia 20 days after a spontaneous delivery. The patient had had an abortion many years earlier.


Lainas T, Zorzovilis I, Petsas G, Alexopoulou E, Lainas G, Ioakimidis T: Osseous metaplasia: case report and review. Fertil Steril 2004, 82: 1433-1435. [6]

Case report of endometrial osseous metaplasia associated with secondary infertility. The lesion was removed hysteroscopically using a resectoscope. The patient then had an in vitro fertilization (IVF) procedure resulting in the delivery of a healthy infant.


Onderoglu LS, Yarali H, Gultekin M, Katlan D: Endometrial osseous metaplasia: an evolving cause of secondary infertility. Fertil Steril 2008, 90: 2013.e9-11. [23]

Patient with secondary infertility after two abortions. Endometrial osseous metaplasia was diagnosed and successfully removed by hysteroscopy.