Figure 3
From: Well-differentiated gall bladder hepatoid carcinoma producing alpha-fetoprotein: a case report
Pathologic examination. Panel A. Gall bladder: Neutrophil and lymphocyte infiltration indicate acute and chronic inflammation compatible with cholecystitis. Panel B. Hepatoid carcinoma with the histologic feature of uniform cells with eosinophilic cytoplasm arranged in a tile-like array or microtrabecular pattern. Infarction necrosis is seen in the right upper field (arrow). Panel C. Viable tumor cells are mostly found surrounding the blood vessels (arrow). Panel D. Immunostaining for alpha-fetoprotein demonstrates varied staining intensity in the cytoplasm of the tumor cells.