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Table 2 Analysis of mutations in the spike protein of the Omicron BA.5.1 SARS-CoV-2 using several bioinformatic tools

From: Urticaria after breakthrough Omicron BA.5.1 severe acute respiratory syndrome coronavirus 2 infection in a triple-vaccinated (Pfizer) patient: a case report

Mutations identified

Description of biological significance

T19I

Amino acid changes that create or remove a potential glycosylation site

L24del, P25del, P26del

Amino acid changes that lead to a deletion of amino acid residues

A27S, G142D, V213G, S375F, T376A, H655Y,

N679K, N764K, D796Y, Q954H, N969K

Amino acid changes occurring more than 100 times that are more interesting epidemiologically

H69del, V70del, G339D, S371F, S373P, D405N, R408S, K417N, N440K, L452R, S477N, T478K, E484A, F486V, Q498R, N501Y, Y505H, D614G, P681H

Amino acid changes that occur at a site known to be involved in phenotypic effects such as altering host-cell receptor binding or antigenicity

Reference: hCoV-19/Wuhan/WIV04/2019 (Wuhan)