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Fig. 2 | Journal of Medical Case Reports

Fig. 2

From: Peripheral precocious puberty in Li–Fraumeni syndrome: a case report and literature review of pure androgen-secreting adrenocortical tumors

Fig. 2

Pathology. A Macroscopic image of the adrenal tumor with an intact thin capsule. Weight 11.2 g (after fixation), dimensions 4.5 cm × 3 × 2.5 cm, and maximum diameter 2.5 cm B Low magnification and C high magnification image of H&E staining showing a solid population of eosinophilic cells with granular cytoplasm, vesicular nuclei with moderate pleomorphism, and some giant nuclei. No hemorrhagic or necrotic zones. D, E Positive immunostaining for (D) inhibin and (E) Melan-A. F Low mitotic activity with a Ki67 positive cell ratio of approximately 10%. G Strong and diffuse P53 immunoexpression (100% of positive cells)

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Journal of Medical Case Reports

ISSN: 1752-1947