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Fig. 3 | Journal of Medical Case Reports

Fig. 3

From: Hemangioblastoma with late leptomeningeal metastasis: a case report

Fig. 3

AF Lateral cerebellar tumor, histologically consistent with hemangioblastoma (A, hematoxylin and eosin stain, 200× magnification). Extramedullary hematopoiesis is seen (A, circle). A high-power image shows hemangioblastoma stromal cells with vacuolated cytoplasm surrounded by thin-walled capillaries ( B, hematoxylin and eosin stain, 400× magnification). Immunohistochemical staining for inhibin is strongly positive in tumor cells (C, 200× magnification). Reticulin stain highlights the delicate capillary network that surrounds the nests of hemangioblastoma stromal cells (D, 200× magnification). Cytokeratin CAM 5.2 (E, 200× magnification) and renal cell carcinoma (RCC, F, 200× magnification) stains are negative in the hemangioblastoma cells, ruling out metastatic renal cell carcinoma

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