Fig. 1

Remarkable increase in triptan-free days directly following COVID-19 disease. Displayed is the number of days per month without triptan consumption from September 2019 to May 2021, based on the recordings of the patient. The number of migraine-free days was identical to the depicted triptan-free days, with the exception of July 2020, when the 57-year-old patient experienced four migraine attacks, without triptan intervention, during a drug holiday associated with 12 days of prednisolone treatment (100 mg on the first 2 days and stepwise reduction to 10 mg on the last two days). The first SARS-CoV-2-positive PCR test was on 21 December 2020. The patient had COVID-19 symptoms until 4 January 2021, and a period of 80 days with only 20 migraine attacks started on 7 January 2021. Starting on 28 March, the patient returned to having almost daily migraine attacks