Table 1 Summary of articles describing children with alpha-gal syndrome
Bircher et al. [5] | Fischer et al. [6] | ||
|---|---|---|---|
Number of children included | 35 | 1 | 107 |
Study country | USA | Switzerland | Germany |
Symptoms | No symptoms associated with alpha-gal sensitization | ||
Hives | 31/35 (89%) | 1/1 (100%) | NR |
Anaphylaxis | 17/35 (49%) | 1/1 (100%) | NR |
Gastrointestinal | 23/35(66%) | 1/1 (100%) | NR |
History of asthma | 10/35 (29%) | 0/1 (0%) | NR |
Tick bite in the last 10 years | 35/35 (100%) | NR | NR |
Αlpha-gal sIgE > 0.35 IU/mL | 34/35 (97%) | 1/1 (100%) | NDa |
Positive basophil activation tests | ND | 1/1 (100%) | ND |