Table 2 Clinical severity score of dengue infection

1. General condition

 a. Ill look, malaise, headache

Score 1

 b. Postural dizziness, cold peripheries, venous collapse

Score 1

2. Hematological

 a. Bleeding (GI, GU, gum bleeding, skin bleeding)

Score 1

 b. Drop of PCV by 5 without clinical

Score 1

 c. Platelet count < 50,000/mcL

Score 1

3. Cardiac

 a. Heart rate > 100

Score 1

 b. Systolic blood pressure < 90 mmHg

Score 1

 c. ECG: diffuse T inversions/ST changes

Score 1

 d. Low ejection fraction in echo

Score 1

4. Pulmonary

 a. Tachypnea RR > 20 cycles/minute

Score 1

 b. SpO₂ < 95%

Score 1

5. Renal

 a. Urine output < 0.5 mL/kg for > 6 hours

Score 1

 b. Rising serum creatinine > 1.5× baseline

Score 1

6. Liver

 a. Rising serum bilirubin ×3 times

Score 1

 b. Transaminases(AST and ALT) > 1000

Score 1

 c. INR > 1.5 or APTT > 1.5 times the control

Score 1

7. Nervous

 a. Drowsy/GCS < 14/15

Score 1

 b. EEG changes

Score 1

8. Venous blood gas parameters

 a. Lactate > 3 mmol/L

Score 1

 b. Venous bicarbonate < 15 mmol/L

Score 1

Total score 20