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Table 1 Reported case studies of iatrogenic spinal hematoma following a lumbar puncture, January 2014–January 2022

From: Multiple lumbar punctures aiming to relieve headache results in iatrogenic spinal hematoma: a case report

Case study

Procedure

Clotting defect

Time to presentation

Pain

Red cell count in CSF (μL)

Hematoma

Management

Outcome

Bi et al., 2021 [22]

Epidural anesthesia

None

Unknown

Unknown

Unknown

SDH

Conservative

Fully recovered

Sawaya et al., 2018 [13]

Epidural anesthesia

Normal clotting bloods but on LMWH with AKI

1 hour

Headache

Unknown

IDH + EDH

Conservative

Unknown

Sawaya et al., 2018 [13]

LP

Normal blood but had myelodysplasia

Few hours

Lower back pain and bilateral thighs

4

IDH

Conservative

Death

Park et al., 2017 [23]

LP

None

Several minutes

Unknown

Unknown

SAH

Surgery

Fully recovered

Kothari et al., 2016 [21]

LP

Yes, mildly decreased fibrinogen only

Several hours

Bilateral legs

Unknown

SAH + SDH

Surgery

Unknown

Avecillas-Chasin et al., 2016 [24]

Spinal anesthesia

Unknown

3 days

Lower back and legs

Unknown

SAH + SDH

Surgery

Mild paraparesis

  1. CSF  cerebrospinal fluid, LP  lumbar puncture, SAH  subarachnoid hematoma, SDH  subdural hematoma, IDH  intradural hematoma, EDH  epidural hematoma, LMWH  low molecular weight heparin, AKI acute kidney injury