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Table 1 Patient monitoring characteristics during cytokine release syndrome adverse event

From: Five-year remission without disease progression in a patient with relapsed/refractory multiple myeloma with extramedullary disease treated with LCAR-B38M chimeric antigen receptor T cells in the LEGEND-2 study: a case report

Characteristic/date

14 June 2016

15 June 2016

16 June 2016

20 June 2016

27 June 2016

Peak body temperature, °C

39

38.9

36.7

Activated partial thromboplastin time, seconds (NR)

43 (23–35)

Within the normal range

Heart rate, beats per minute

180

88

Cytokine profile

hIL-6, pg/mL (NR < 3.4)

314.00

37.40

27.40

hIL-8, pg/mL (NR < 14)

92.70

133.00

26.20

hIL-10, pg/mL (NR < 9.1)

392.00

50.30

Normal

TNF-α, pg/mL (NR < 8.1)

52.10

42.50

22.00

  1. h, human; IL, interleukin; NR, normalized ratio; TNF, tumor necrosis factor