Table 2 Patient characteristics in prior cases reporting an association between AoSD and CG
From: The association between adult-onset Still’s disease and collapsing glomerulopathy: a case report
Case 1 [4] | Case 2 [5] | Case 3 [6] | |
|---|---|---|---|
Age (years)/Sex/Race | 18/Female/African American | 32/Male/African American | 46/Female/African American |
Serum creatinine (mg/dL) | 0.76 | 5.15 | 2.5 |
Serum albumin (g/dL) | Unknown | 4.1 | 3.1 |
Urine protein/creatinine ratio (g/g) | 0.19 | 19.98 | 5.1 |
Renal biopsy | Collapsing glomerulopathy | Collapsing glomerulopathy | Collapsing glomerulopathy |
Fever | Yes | Yes | Yes |
Arthralgias/arthritis | Yes | Yes | Yes |
Salmon rash | Yes | Yes | No |
Leukocytosis | No | Yes | Yes |
Sore throat | No | Unknown | No |
Lymphadenopathy | Yes | Yes | Yes |
Hepatomegaly/splenomegaly | No | Yes | Yes |
AST/ALT/LDH elevation | No | Yes | Yes |
ANA/RF serologies | Negative | ANA 1:1280/RF unknown | Negative |
Treatment | PO prednisone 1 mg/kg/day and ACE-I | IVIG 0.4 g/kg daily for 5 days and mycophenolate mofetil 1 g BID | Prednisolone 40 mg/day |
Clinical improvement | Yes | Yes | Yes |