Table 1 Patient characteristics at various timepoints of disease course
From: The association between adult-onset Still’s disease and collapsing glomerulopathy: a case report
Nephrotic syndrome presentation | Nephrotic syndrome remission | AoSD presentation | Rheumatology follow-up | Death | |
|---|---|---|---|---|---|
Age (years) | 15 | 16–27 | 27 | 27–30 | 30 |
White blood count (4–10 K/μL) | 5.07 | 2.5–11.05 | 18.74 | 3.2–14.18 | 30.39 |
Hemoglobin (12–16 g/dL) | 13.2 | 11.9–14.8 | 9.7 | 9.8–14.9 | 7.7 |
Platelet count (150–399 K/μL) | 296 | 169–320 | 478 | 143–293 | 121 |
Serum creatinine (0.65–1.00 mg/dL) | 2.4 | 1.1 | 2.95 | 1.52–4.87 | 17.33 |
Serum albumin (3.5–5.0 g/dL) | 1.9 | 3.9 | 1.4 | 2.3–3.9 | 1.4 |
Urine protein/creatinine ratio (0.021–0.161 g/g) | 12.2 | < 1 | 5.4 | 0.81–2.2 | 6.9 |
Urinalysis | Protein > 300, moderate blood, 5 WBC, 5 RBC, no casts | Protein 30, no blood, no WBC/RBC, no casts | Protein > 300, large blood, 10 WBC, 5 RBC, no casts | Protein 30, no blood, no WBC/RBC, no casts | Protein > 600, large blood, 1 WBC, 9 RBC, no casts |
Renal biopsy | Collapsing glomerulopathy | Not applicable | Collapsing glomerulopathy | No further biopsies | No further biopsies |
Fever | No | No | Yes | Intermittently | Yes |
Arthralgias/arthritis | No | No | Yes | Intermittently | Yes |
Salmon rash | No | No | No | No | No |
Sore throat | No | No | Yes | Intermittently | No |
Lymphadenopathy | No | No | Yes | No | Yes |
Hepatomegaly/splenomegaly | No | No | No | No | Yes |
AST/ALT/LDH elevation | No | No | Yes (364/173/695) | Intermittently | Yes (488/49/1310) |
Ferritin (ng/mL) | Not assessed | Not assessed | > 40,000 | 148–2116 | 8749 |
ANA/RF serologies | ANA 1:80 speckled, RF < 20 | No serologies | ANA 1:80 homogenous, RF 62 | No serologies | ANA < 1:40, RF 16 |
Microbiology | HIV and parvovirus B19 negative | Not applicable | HIV, EBV, CMV, influenza, histoplasmosis, hepatitis B and C, RPR, and quantiferon gold negative | Not applicable | COVID-19, quantiferon gold, and C. diff toxin negative |
Blood cultures | Not applicable | Not applicable | Blood culture ×3 negative | Not applicable | Blood culture ×2 negative |