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Table 1 Laboratory values along the clinical course, upon presentation, and after the different therapeutic strategies

From: Treatment-related hemophagocytic lymphohistiocytosis due to atezolizumab: a case report and review of the literature

 

Presentation

Day 3 (48 hours after steroids)

Day 5 after MMF, anakinra, tocilizumab, and etoposide

White blood cells, k/cumm

2.58

3.08

1.92

Lymphocytes, k/cumm

1.2

2.3

0.7

Hemoglobin, g/dL

7.1

7.4

6.4

Reticulocytes (absolute)

0.0128

  

Platelets, k/cumm

25

23

17

AST, U/mL

122

  

ALT, U/mL

108

201

305

Creatinine, mg/dL

1.16

0.9

0.7

Total bilirubin, mg/dL

3.2

1.8

1.3

Indirect bilirubin, mg/dL

0.1

0.4

0.4

Triglycerides, mg/dL

151

  

CRP, mg/dL

14.18

5.1

1.4

Ferritin, ng/dL

7035

  

Fibrinogen, mg/dL

507

244

133

D-dimer

9042

8309

7357

sIL-2R (CD25), U/mL

6516

  

IL-6, pg/dL

19.4

  
  1. K/cumm cells per microliter, MMF mycophenolate mofetil, g/dL grams per deciliter, AST aspartate aminotransferase, U/mL units per mililiter, ALT alaline transaminase, mg/dL miligrams per deciliter, CRP C reactive protein, ng/mL nanograms per mililiter, sIL-2R soluble interleukin-2 receptor, CD25 cluster of differentiation protein 25, IL-6 interleukin 6, pg/ml picograms per mililiter
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Journal of Medical Case Reports

ISSN: 1752-1947