From: Fungal keratitis caused by Scedosporium apiospermum: a case report
Time (days) | Day 0 | Day 6 | Day 22 | Day 60 | Day 730 |
---|---|---|---|---|---|
Visual acuity (Snellen chart) | Counting fingers at 30 cm | 20/400 | 20/40 | 20/25 | 20/25 |
Findings | A 3 × 3 mm corneal abscess with hypopyon | The hypopyon regressed | A 2 × 2 mm corneal abscess | The corneal abscess regressed with minimal haze | The cornea was transparent |
Treatment | FF gentamicin and FF cefazolin drops 24 times per day Intravenous fluconazole 1 × 800 mg loading, 1 × 400 mg maintenance dose Intravenous vancomycin 4 × 500 mg Intravenous cefoperazone + sulbactam 2 × 2 g | FF vancomycin, ceftazidime voriconazole drops 24 times per day Intravenous voriconazole 2 × 6 mg/kg loading and 2 × 4 mg/kg maintenance dose | FF vancomycin, ceftazidime voriconazole drops 8 times per day Oral voriconazole 200 mg 2 × 1 | Treatment stopped | No treatment |