Skip to main content

Table 1 Diagnostic criteria of hypocomplementemic urticarial vasculitis syndrome from McDuffie et al. for the diagnosis of HUVS, two major criteria and at least two minor criteria should be present [6]

From: Correct approach in urticarial vasculitis made early diagnosis of lupus nephritis possible: a case report

Major criteria

1. Urticarial vasculitic skin lesions

2. Low levels of serum complement (all components)

Minor criteria

1. Venulitis of the dermis on biopsy

2. Arthritis or arthralgia

3. Glomerulonephritis

4. Episcleritis or uveitis

5. Recurrent abdominal pain

6. A positive C1q precipitin test by immunodiffusion with an associated suppressed C1q level

  1. Exclusion criteria are significant cryoglobulinemia (cryocrit > 1%), an elevated anti-DNA antibody titer, a high titer of antinuclear antibody (ANA), hepatitis B antigenemia, and hereditary deficiency of a complement component or of C1 esterase inhibitor
Back to article page

Journal of Medical Case Reports

ISSN: 1752-1947