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Table 4 Literature review

From: Acute benign pleural effusion, a rare presentation of hepatitis A virus: a case report and review of the literature

Study

Imaging finding

HAV serology

INR

Albumin (g/dl)

Total/direct bilirubin (mg/dl)

Pleural fluid analysis

Saha [15]

USG: bilateral pleural effusion, ascites

CXR: left-sided pleural effusion

Serum anti-HAV IgM positive

N/A

2.9

5.6/5

NA

Roy [16]

Case 1

USG: hepatomegaly, ascites, bilateral pleural effusion

CXR: bilateral pleural effusion (right > left)

Serum and pleural fluid anti-HAV IgM positive

N/A

3.4

2.6/1.4

Total cell count 1500, glucose 99 mg/dl and protein 4.1 g/dl, negative culture

Roy [16]

Case 2

USG: hepatomegaly, ascites, bilateral pleural effusion

CXR: bilateral pleural effusion (right > left)

Serum anti-HAV IgM positive

N/A

3.2

6.2/6.2

NA

Owen [17]

CXR: right pleural effusion

NA

N/A

N/A

N/A

NA

Dalai et al. [14]

USG: right-sided pleural effusion, ascites, hepatomegaly

Serum anti-HAV IgM positive

2

N/A

3.5/1.5

NA

Nagarajan et al. [17] Case 1

USG: hepatomegaly, ascites, bilateral pleural effusion

CXR: bilateral pleural effusion (right > left)

Serum and pleural fluid anti-HAV IgM positive

N/A

2.5

5.4/4.8

Total cell count 0, protein 20 g/dl

Nagarajan et al. [17] case 2

USG: hepatomegaly, bilateral pleural effusion, ascites

CXR: bilateral pleural effusion

Serum anti-HAV IgM positive

N/A

3.2

6.9/5.9

NA

Allen et al. [18]

USG: ascites, diffuse gallbladder wall thickening

CT: ascites, right-side pleural effusion, gallbladder wall thickening

Serum anti-HAV IgM positive

N/A

3.6

6/2.4

NA

Selimoğlu et al. [19]

USG: hepatomegaly CXR: right lower lung consolidation

Serum and pleural fluid anti-HAV IgM positive

1.25

3.5

6/3.5

Total cell count 0, glucose 70 mg/dl and protein 4.5 g/dl, negative culture

Mehta et al. [13]

CXR: right-side pleural effusion

Serum and pleural fluid anti-HAV IgM positive

N/A

2.8

5.3/5.2

Total cell count 18200, glucose 94 mg/dl and protein 7.7 g/dl, negative culture

Alhan et al. [14]

USG: hepatomegaly, right-side pleural effusion

Serum and pleural fluid anti-HAV IgM positive

N/A

4.0

3.9/2.6

Total cell count 0, transudate

Erdem et al. [20]

USG: ascites, right-side pleural effusion, thickened gallbladder wall; CXR: right-sided pleural effusion

Serum and pleural fluid anti-HAV IgM, positive

1.1

1.9

6.3/5.6

Total cell count 0, transudate

Ghosh and Kundu [12]

CXR: middle and lower zones of left lung opacity

MRI: pleural effusion, hepatosplenomegaly, thickened gallbladder wall

Serum and pleural fluid anti-HAV IgM positive

1.9

N/A

5.6/5.5

Exudative pleural effusion

Gürkan et al. [10]

USG: ascites

CXR: bilateral pleural effusion

Serum anti-HAV IgM positive

N/A

3.6

6/2.5

NA

Kaman et al. [10]

USG: ascites, pleural effusion

CXR: right-side pleural effusion

Serum anti-HAV IgM positive

N/A

2.5

6.6/4.8

Glucose 90 mg/dl, negative culture

Vaidya et al. [21]

USG: ascites, hepatomegaly, bilateral pleural effusion

CXR: left-side pleural effusion

Serum anti-HAV IgM positive

1.1

4

5.2/4.2

NA

Bukulmez et al. [22]

USG: hepatomegaly, right-side pleural effusion

CT: right pleural effusion

Serum anti-HAV IgM positive

1

3.3

8.2/6.7

NA

Dhakal et al. [5]

USG: ascites, bilateral pleural effusion

CXR: right-side pleural effusion

Serum anti-HAV IgM positive

N/A

N/A

5.8/4.5

NA

Hadgu et al. [24]

USG: mild ascites, hepatosplenomegaly, and small bilateral pleural effusion

Serum anti-HAV IgM positive

1.5

3.8

1.5/0.5

No cells, lactic acid dehydrogenase 15 IU/l, negative TB, negative bacterial culture

Iza et al. [25]

USG: right pleural effusion, ascites and acalculous cholecystitis

Serum anti-HAV IgM positive

Normal

3.5

2.6/2.5

N/A

  1. F: Female, M: Male, Y: Years, M: months, N/A: not available, USG: ultrasonography, CXR: chest x-ray, CT: Computed tomography, MRI: Magnetic resonance imaging