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Table 2 Cases of acute pancreatitis associated with drugs related to weightlifting or bodybuilding

From: Drug-induced acute pancreatitis in a bodybuilder: a case report

Case

Patient

Findings

Drug(s) taken

Delay between introduction of the drug and pancreatitis

Rechallenge

Outcome

Safizadeh Shabestari et al. 2021 (our case)

31-year-old male

Elevated amylase and lipase, with CT abdomen showing pancreatitis

Fluoxymesterone, mesterolone, drostanolone propionate, stanozolol, tamoxifen, testosterone enanthate, testosterone propionate, clenbuterol, and growth hormone

1 month

Not performed

Clinical improvement with fluid hydration and pain management

Kumar et al. [16]

24-year-old male

Elevated amylase and lipase, with CT abdomen showing pancreatitis

Trenbolone acetate

Several months

Not performed

Clinical improvement with conservative treatment

Binet et al. [27]

28-year-old male

Isolated elevation of lipase, with CT abdomen showing pancreatitis

l-Arginine alpha-ketoglutarate and other vitamins and supplements

18 months

Not performed

Clinical improvement with conservative treatment

Liane et al. 2016 [5]

20-year-old male

Elevated amylase and lipase, LDH, and CK, with CT abdomen showing pancreatitis

Anabolic–androgenic steroid called “Guerilla Warfare”

1 month

Not performed

Clinical improvement with fluid hydration and pain management

Garg [17]

28-year-old male

Elevated amylase and lipase, with ultrasonography abdomen showing pancreatitis

Anabolic–androgenic steroid

Data unavailable

Not performed

Patient died

Rosenfeld et al. [28]

50-year-old male

Elevated lipase and triglycerides, with CT abdomen showing pancreatitis

Methandrostenolone

2 months

Not performed

Supportive therapy

Schäfer et al. [29]

26-year-old male

Hypercalcemia and elevated lactate dehydrogenase and pancreatic amylase, with CT abdomen showing pancreatitis

Oxymetholone, nandrolone decanoate, testosterone, epitestosterone, and erythropoietin

After second annual injection cycle

Not performed

Aggressive intravenous rehydration, transferred to intensive care unit because of anuria

Samaha et al. [2]

24-year-old male

Leukocytosis with left shift, hypercalcemia, and elevated amylase, lipase, and CPK

Testosterone

2 months

Not performed

Slow clinical improvement with fluid hydration and pain management

Rutten et al. [21]

40-year-old male

Elevated amylase and CRP with abdominal ultrasonography

Growth hormone

2 weeks

Not performed

Conservative treatment

Saka et al. [15]

16-year-old male

Elevated amylase and lipase with CT abdomen showing pancreatitis

l-Arginine and zinc

5 months

Not performed

Clinical improvement with ciprofloxacin, fluids, and bowel rest